Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Choose more journals

Article type Check one or more article types to show results from those article types only.
Subject Check one or more subjects to show results from those subjects only.
Date Choose a date option to show results from those dates only.

Custom date range

Clear all filters
Sort by:
Showing 1–6 of 6 results
Advanced filters: Author: Pavithra Aravamudhan Clear advanced filters

  • The reovirus outercapsid protein σ1 binds to α-linked sialic acid and junctional adhesion molecule A (JAM-A) for virus entry. Here, combining atomic force microscopy and confocal microscopy, the authors provide insights into the dynamics of these interactions at the single-virion level in living cells.

    • Melanie Koehler
    • Pavithra Aravamudhan
    • David Alsteens
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-14

  • Mammalian orthoreovirus causes serotype-specific disease in the brain. Here, Shang et al. identify and characterise the role of paired immunoglobulin-like receptor B in reovirus attachment, entry and infectivity in the brain.

    • Pengcheng Shang
    • Joshua D. Simpson
    • Terence S. Dermody
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-15

  • Reovirus endocytosis depends on junctional adhesion molecule A (JAM-A) and β1 integrin binding. Here, Koehler et al. use single-virus force spectroscopy and confocal microscopy to demonstrate a direct interaction between reovirus and β1 integrins via viral capsid protein λ2, which promotes clathrin recruitment to cell-bound reovirus.

    • Melanie Koehler
    • Simon J. L. Petitjean
    • David Alsteens
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-15

  • The spliceosome is a complex small nuclear RNA–protein machine that removes introns from pre-mRNAs. A single-molecule fluorescence resonance emission transfer (FRET) assay using the efficiently spliced yeast pre-mRNA, Ubc4, reveals many reversible, time- and ATP-dependent changes in conformation for individual pre-mRNAs and indicates that spliceosome assembly occurs close to thermal equilibrium.

    • John Abelson
    • Mario Blanco
    • Nils G Walter
    Research
    Nature Structural & Molecular Biology
    Volume: 17, P: 504-512