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Showing 1–5 of 5 results
Advanced filters: Author: Pawel Burkhardt Clear advanced filters

  • Multisystem inflammatory syndrome following SARS-CoV-2 infection results from increased serum levels of TGFβ, which impairs the reactivation of virus-specific T cells.

    • Carl Christoph Goetzke
    • Mona Massoud
    • Mir-Farzin Mashreghi
    ResearchOpen Access
    Nature
    Volume: 640, P: 762-771

  • The physical organization of the genome in non-bilaterian animals and their closest unicellular relatives is characterized; comparative analysis shows chromatin looping is a conserved feature of genome architecture and spatial genome regulation emerged early in animal evolution.

    • Iana V. Kim
    • Cristina Navarrete
    • Arnau Sebé-Pedrós
    ResearchOpen Access
    Nature
    Volume: 642, P: 1097-1105

  • The evolutionary point where chromatin modifier function integrated into regulation of specific cell types is unclear. In the cnidarian Nematostella vectensis, the authors here show that lysine specific demethylase Lsd1 is developmentally regulated and required for normal development including cnidocyte differentiation.

    • James M. Gahan
    • Ian U. Kouzel
    • Fabian Rentzsch
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-13

  • Genome analysis and molecular cell biology studies indicate that SPIRE actin nucleators originated in unicellular ancestors of animals, providing an actin-myosin driven exocytic transport mechanism that may have contributed to animal evolution.

    • Martin Kollmar
    • Tobias Welz
    • Eugen Kerkhoff
    ResearchOpen Access
    Communications Biology
    Volume: 7, P: 1-21