Tuberculosis (TB) continues to cause considerable morbidity and mortality worldwide and there is an urgent need for novel therapies and treatment regimens of shorter duration. Here, Zumla, Nahid and Cole discuss current concepts and recent advances in TB drug discovery, development and clinical trial evaluation, and provide an update of new agents and approaches currently being investigated.
- Alimuddin Zumla
- Payam Nahid
- Stewart T. Cole