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Advanced filters: Author: Pei-Hsien Ren Clear advanced filters

  • Fibrillar polyglutamine aggregates are taken up by mammalian cells in culture and associate with aggresomes that contain both proteasome subunits and chaperones. Aggresomes also recruit soluble proteins that share the same amyloidogenic sequences as the internalised polyglutamine aggregates.

    • Pei-Hsien Ren
    • Jane E. Lauckner
    • Ron R. Kopito
    Research
    Nature Cell Biology
    Volume: 11, P: 219-225