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Showing 1–7 of 7 results
Advanced filters: Author: Peter Blankestijn Clear advanced filters

  • Previous studies have indicated that ablation of renal sympathetic nerves reduces blood pressure in patients with resistant hypertension and preserved renal function. Hering et al. have now investigated the efficacy and safety of this procedure in patients with moderate to severe chronic kidney disease.

    • Peter J. Blankestijn
    • Jaap A. Joles
    News & Views
    Nature Reviews Nephrology
    Volume: 8, P: 439-440

  • Uncontrolled hypertension is an important clinical problem and is associated with considerable morbidity and mortality. A new report from the SPYRAL HTN-OFF MED researchers, which describes the use of renal denervation in patients with uncontrolled hypertension, might reignite enthusiasm for this technique, while a first-in-human description of endovascular baroreflex amplification from the CALM-FIM_EUR investigators highlights the potential of this new approach to inhibit sympathetic activity.

    • Peter J. Blankestijn
    • Michiel L. Bots
    News & Views
    Nature Reviews Nephrology
    Volume: 13, P: 725-726

  • Health-care professionals in general and nephrologists in particular can and should make clear contributions towards achieving the Sustainable Development Goals. This commitment will require changes in patient care, research and education, which should be carried out in collaboration with relevant stakeholders, such as health-care industries.

    • Peter J. Blankestijn
    Comments & Opinion
    Nature Reviews Nephrology
    Volume: 17, P: 7-8

  • This wide-ranging introduction to new technologies for the management of renal failure touches on the optimization of conventional dialysis and on alternative techniques such as transplantation methods, artificial kidneys, tissue engineering strategies and harnessing the regenerative capacity of stem cells. The potential for other organs to 'host' renal functions, and the co-opting of developmental plasticity, are also discussed.

    • Branko Braam
    • Marianne C Verhaar
    • Jaap A Joles
    Reviews
    Nature Clinical Practice Nephrology
    Volume: 3, P: 564-572

  • A meta-analysis of individual-level patient data from 66 clinical studies supports the utility of glomerular filtration rate as a surrogate endpoint in clinical trials for chronic kidney disease, with potential to enable detection of events earlier in the disease course.

    • Lesley A. Inker
    • Willem Collier
    • Mauro Saddelli
    Research
    Nature Medicine
    Volume: 29, P: 1867-1876