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Showing 1–24 of 24 results

Advanced filters: Author: Peter Manza Clear advanced filters

Methylphenidate reorganizes cortical hierarchy through dopaminergic modulation

Here, the authors show that methylphenidate alters brain organization by compressing the hierarchy between sensory and association areas. This dopamine-driven shift predicts improved attention, revealing how stimulants reorganize brain networks to enhance cognitive function.

Dardo Tomasi
Peter Manza
Nora D. Volkow
ResearchOpen Access13 Dec 2025
Nature Communications

Volume: 17, P: 1-16
Chronic cannabis users show deficits in gray and white matter structure

Peter Manza
Kai Yuan
Nora D. Volkow
Research03 Dec 2020
Molecular Psychiatry

Volume: 25, P: 3115
Neural circuit selective for fast but not slow dopamine increases in drug reward

The faster a drug enters the brain, the greater its addictive potential. Using simultaneous PET-fMRI in humans, here the authors report a neural circuit responding to fast but not slow dopamine increases from intravenous versus oral methylphenidate delivery.

Peter Manza
Dardo Tomasi
Nora D. Volkow
ResearchOpen Access08 Nov 2023
Nature Communications

Volume: 14, P: 1-11
Response inhibition in Parkinson’s disease: a meta-analysis of dopaminergic medication and disease duration effects

Peter Manza
Matthew Amandola
Hoi-Chung Leung
ReviewsOpen Access07 Jul 2017
npj Parkinson's Disease

Volume: 3, P: 1-10
Stimulant medications in children with ADHD normalize the structure of brain regions associated with attention and reward

Feifei Wu
Wenchao Zhang
Yi Zhang
Research26 Feb 2024
Neuropsychopharmacology

Volume: 49, P: 1330-1340
Brain connectivity changes to fast versus slow dopamine increases

Peter Manza
Dardo Tomasi
Nora D. Volkow
ResearchOpen Access07 Feb 2024
Neuropsychopharmacology

Volume: 49, P: 924-932
Cortical D1 and D2 dopamine receptor availability modulate methylphenidate-induced changes in brain activity and functional connectivity

Joint PET and MRI analyses of cortical D1 and D2 dopamine receptors in healthy adults provide a framework for understanding how dopamine-boosting drugs alter brain function.

Peter Manza
Ehsan Shokri-Kojori
Nora D. Volkow
ResearchOpen Access30 May 2022
Communications Biology

Volume: 5, P: 1-9
Sex differences in methylphenidate-induced dopamine increases in ventral striatum

Peter Manza
Ehsan Shokri-Kojori
Nora D. Volkow
ResearchOpen Access27 Oct 2021
Molecular Psychiatry

Volume: 27, P: 939-946
Brain structural changes in cannabis dependence: association with MAGL

Peter Manza
Kai Yuan
Nora D. Volkow
ResearchOpen Access06 Nov 2019
Molecular Psychiatry

Volume: 25, P: 3256-3266
Correction: Striato-cortical tracts predict 12-h abstinence-induced lapse in smokers

Kai Yuan
Meng Zhao
Jie Tian
Amendments and Corrections12 Mar 2019
Neuropsychopharmacology

Volume: 44, P: 1338
Disrupted brain state dynamics in opioid and alcohol use disorder: attenuation by nicotine use

Rui Zhang
Weizheng Yan
Nora D. Volkow
Research07 Nov 2023
Neuropsychopharmacology

Volume: 49, P: 876-884
Time-varying SUVr reflects the dynamics of dopamine increases during methylphenidate challenges in humans

Combined PET imaging and mathematical simulations reveal that the rate of dopamine increase in the striatum underlies self-reports of drug “high” in response to oral and intravenous methylphenidate challenges in humans

Dardo Tomasi
Peter Manza
Nora D. Volkow
ResearchOpen Access10 Feb 2023
Communications Biology

Volume: 6, P: 1-10
Striatal D1 and D2 receptor availability are selectively associated with eye-blink rates after methylphenidate treatment

PET imaging in human participants revealed that D1 and D2 dopamine receptor availability was associated with eye-blink rates following treatment with oral methylphenidate, but not a placebo.

Şükrü B. Demiral
Peter Manza
Nora D. Volkow
ResearchOpen Access26 Sept 2022
Communications Biology

Volume: 5, P: 1-10
Socioeconomic status, BMI, and brain development in children

Evan Dennis
Peter Manza
Nora D. Volkow
ResearchOpen Access24 Jan 2022
Translational Psychiatry

Volume: 12, P: 1-10
Sleep disturbances are associated with cortical and subcortical atrophy in alcohol use disorder

Rui Zhang
Dardo Tomasi
Nora D. Volkow
ResearchOpen Access16 Aug 2021
Translational Psychiatry

Volume: 11, P: 1-11
Relationship between BMI and alcohol consumption levels in decision making

Khushbu Agarwal
Sukru Baris Demiral
Paule Valery Joseph
ResearchOpen Access06 Aug 2021
International Journal of Obesity

Volume: 45, P: 2455-2463
Contrasting dorsal caudate functional connectivity patterns between frontal and temporal cortex with BMI increase: link to cognitive flexibility

Jizheng Zhao
Peter Manza
Dongjian He
Research25 Aug 2021
International Journal of Obesity

Volume: 45, P: 2608-2616
Inhibition of food craving is a metabolically active process in the brain in obese men

Gene-Jack Wang
Ehsan Shokri Kojori
Nora D. Volkow
ResearchOpen Access18 Nov 2019
International Journal of Obesity

Volume: 44, P: 590-600
Ghrelin reductions following bariatric surgery were associated with decreased resting state activity in the hippocampus

Yi Zhang
Gang Ji
Gene-Jack Wang
Research18 Jun 2018
International Journal of Obesity

Volume: 43, P: 842-851
Akinetic rigid symptoms are associated with decline in a cortical motor network in Parkinson’s disease

Sarah J. Kann
Chiapei Chang
Hoi-Chung Leung
ResearchOpen Access24 Aug 2020
npj Parkinson's Disease

Volume: 6, P: 1-8
Methylphenidate’s effects on thalamic metabolism and functional connectivity in cannabis abusers and healthy controls

Şükrü Barış Demiral
Dardo Tomasi
Nora D. Volkow
Research01 Dec 2018
Neuropsychopharmacology

Volume: 44, P: 1389-1397
Striato-cortical tracts predict 12-h abstinence-induced lapse in smokers

Kai Yuan
Meng Zhao
Jie Tian
Research15 Aug 2018
Neuropsychopharmacology

Volume: 43, P: 2452-2458
Neuropsychosocial markers of binge drinking in young adults

Joshua L. Gowin
Peter Manza
Nora D. Volkow
Research12 May 2020
Molecular Psychiatry

Volume: 26, P: 4931-4943
Brain functional and structural magnetic resonance imaging of obesity and weight loss interventions

Guanya Li
Yang Hu
Gene-Jack Wang
ReviewsOpen Access14 Mar 2023
Molecular Psychiatry

Volume: 28, P: 1466-1479