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Stochastic neuropeptide signals compete to calibrate the rate of satiation

Release of hunger-promoting and satiety-promoting neuropeptides drives opposing changes in the second messenger cAMP in awake mouse paraventricular hypothalamic MC4R neurons, thereby regulating synaptic plasticity and the transition to satiety with each bite of food.

Stephen X. Zhang
Angela Kim
Mark L. Andermann
Research06 Nov 2024
Nature

Volume: 637, P: 137-144
Genetically encoded calcium indicator illuminates calcium dynamics in primary cilia

By targeting calcium indicators to primary cilia, micrometer-long protrusions from the cellular plasma membrane, the authors measure Ca²⁺ signaling in these sensory organelles.

Steven Su
Siew Cheng Phua
Takanari Inoue
Research22 Sept 2013
Nature Methods

Volume: 10, P: 1105-1107
Covalent Epitope Decoration of Carbon Electrodes using Solid Phase Peptide Synthesis

Lindsay Candelaria
Peter N. Kalugin
Nikolai G. Kalugin
ResearchOpen Access28 Nov 2019
Scientific Reports

Volume: 9, P: 1-11
Defining diurnal fluctuations in mouse choroid plexus and CSF at high molecular, spatial, and temporal resolution

The choroid plexus (ChP) modulates cerebrospinal fluid (CSF) composition and the blood-CSF barrier. Here the authors show that the ChP is a critical circadian component with time-of-day variations in translation, barrier, and metabolism to alter CSF composition.

Ryann M. Fame
Peter N. Kalugin
Maria K. Lehtinen
ResearchOpen Access22 Jun 2023
Nature Communications

Volume: 14, P: 1-20

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Stochastic neuropeptide signals compete to calibrate the rate of satiation

Genetically encoded calcium indicator illuminates calcium dynamics in primary cilia

Covalent Epitope Decoration of Carbon Electrodes using Solid Phase Peptide Synthesis

Defining diurnal fluctuations in mouse choroid plexus and CSF at high molecular, spatial, and temporal resolution

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