Nature Search

Methicillin-resistant Staphylococcus aureus alters cell wall glycosylation to evade immunity

Strains of methicillin-resistant Staphylococcus aureus use a prophage-encoded glycosyltransferase to alter the glycosylation of their wall teichoic acid and thereby evade antibody-mediated immune responses.

David Gerlach
Yinglan Guo
Andreas Peschel
Research21 Nov 2018
Nature

Volume: 563, P: 705-709
Gating and modulation of a hetero-octameric AMPA glutamate receptor

Analyses of AMPA receptor–auxiliary subunit complexes provide insights into the gating and modulation of the AMPA receptor by TARP-γ8 and CNIH2.

Danyang Zhang
Jake F. Watson
Ingo H. Greger
Research02 Jun 2021
Nature

Volume: 594, P: 454-458
Identification of epilepsy-associated neuronal subtypes and gene expression underlying epileptogenesis

The pathophysiology of epilepsy is unclear. Here, the authors present single-nuclei transcriptomic profiling of human temporal lobe epilepsy from patients. They identified epilepsy-associated neuronal subtypes, and a panel of dysregulated genes, predicting neuronal circuits contributing to epilepsy.

Ulrich Pfisterer
Viktor Petukhov
Konstantin Khodosevich
ResearchOpen Access07 Oct 2020
Nature Communications

Volume: 11, P: 1-19
Whole-genome analysis of diverse Chlamydia trachomatis strains identifies phylogenetic relationships masked by current clinical typing

Simon Harris and colleagues report whole-genome sequencing of 36 Chlamydia trachomatis representative strains from temporally and geographically diverse sources and use this to construct a genome-wide phylogeny of the species. They find that epidemic spread can be driven by clonal expansion from a single source and also report evidence for recombination in recent clinical strains both within and between biovars.

Simon R Harris
Ian N Clarke
Nicholas R Thomson
Research11 Mar 2012
Nature Genetics

Volume: 44, P: 413-419
Diminishing benefits of urban living for children and adolescents’ growth and development

The advantage of living in cities compared with rural areas with respect to height and BMI in children and adolescents has generally become smaller globally from 1990 to 2020, except in sub-Saharan Africa.

Anu Mishra
Bin Zhou
Majid Ezzati
ResearchOpen Access29 Mar 2023
Nature

Volume: 615, P: 874-883
Dendritic structural plasticity and neuropsychiatric disease

The morphology of dendrites and dendritic spines changes with development and as a result of activity-dependent plasticity mechanisms. Penzes and colleagues describe the altered dendritic structural plasticity that is associated with some neuropsychiatric disorders and consider the underlying molecular mechanisms, based on recent genetic discoveries.

Marc P. Forrest
Euan Parnell
Peter Penzes
Reviews16 Mar 2018
Nature Reviews Neuroscience

Volume: 19, P: 215-234
A revised view of the role of CaMKII in learning and memory

The CaMKII holoenzyme was long thought to mediate memory storage via an autophosphorylation reaction that occurs between its subunits at Thr286 (pThr286). This Perspective explains shortcomings of earlier models and provides an updated view.

Karl Ulrich Bayer
Karl Peter Giese
Reviews18 Nov 2024
Nature Neuroscience

Volume: 28, P: 24-34
Aberrant phase separation and nucleolar dysfunction in rare genetic diseases

Frameshift mutations that create arginine-rich basic tails in transcription factors and other proteins can lead to altered phase separation in the nucleolus, which in turn leads to syndromes such as brachyphalangy, polydactyly and tibial aplasia.

Martin A. Mensah
Henri Niskanen
Denes Hnisz
ResearchOpen Access08 Feb 2023
Nature

Volume: 614, P: 564-571
Rescue of neuropsychiatric phenotypes in a mouse model of 16p11.2 duplication syndrome by genetic correction of an epilepsy network hub

The 16p11.2 duplication confers risk for autism and schizophrenia, but the disease mechanisms are unknown. Here, the authors use proteomics to show dysregulation of synaptic and epilepsy-associated protein networks in the cortex of model mice, and demonstrate that correcting Prrt2 gene dosage rescues circuit hypersynchrony and behavioural phenotypes.

Marc P. Forrest
Marc Dos Santos
Peter Penzes
ResearchOpen Access17 Feb 2023
Nature Communications

Volume: 14, P: 1-20
Plant traits and associated ecological data from Afromontane grasslands of Maloti-Drakensberg, South Africa

Aud H. Halbritter
Vigdis Vandvik
Brian J. Enquist
ResearchOpen Access12 Nov 2025
Scientific Data

Volume: 12, P: 1-27
Rising rural body-mass index is the main driver of the global obesity epidemic in adults

Contrary to the view that urbanization is a major driver of the global rise in obesity, the global increase in body-mass index is shown to be mostly due to increases in the body-mass indexes of rural populations.

Honor Bixby
James Bentham
Majid Ezzati
ResearchOpen Access08 May 2019
Nature

Volume: 569, P: 260-264
Ant-plant sociometry in the Azteca-Cecropia mutualism

Peter R. Marting
Nicole M. Kallman
Stephen C. Pratt
ResearchOpen Access19 Dec 2018
Scientific Reports

Volume: 8, P: 1-15
Ancient DNA study reveals HLA susceptibility locus for leprosy in medieval Europeans

Leprosy, caused by infection with Mycobacterium leprae, was common in Europe in the Middle Ages. Here, Krause-Kyora et al. analyze ancient DNA from a medieval Danish leprosarium to assemble 10 complete bacterial genomes and perform association analysis of the DRB1*15:01 allele with risk of leprosy infection.

Ben Krause-Kyora
Marcel Nutsua
Almut Nebel
ResearchOpen Access01 May 2018
Nature Communications

Volume: 9, P: 1-11
Neratinib protects pancreatic beta cells in diabetes

Type 1 as well as type 2 diabetes are characterized by a loss of insulin-producing β-cells. Here the authors show that the FDA-approved drug neratinib has beneficial effects on β-cell survival, insulin secretion, and glycemic control in mouse models of diabetes.

Amin Ardestani
Sijia Li
Kathrin Maedler
ResearchOpen Access01 Nov 2019
Nature Communications

Volume: 10, P: 1-17
Recycling pathways in cold-water coral reefs: Use of dissolved organic matter and bacteria by key suspension feeding taxa

Sandra R. Maier
Tina Kutti
Dick van Oevelen
ResearchOpen Access18 Jun 2020
Scientific Reports

Volume: 10, P: 1-13
Comparison of trace element chemistry in human bones interred in two private chapels attached to Franciscan friaries in Italy and Denmark: an investigation of social stratification in two medieval and post-medieval societies

Kaare Lund Rasmussen
Thomas Delbey
Per Orla Thomsen
ResearchOpen Access02 Jul 2020
Heritage Science

Volume: 8, P: 1-21
Convento di San Francesco a Folloni: the function of a Medieval Franciscan Friary seen through the burials

Marielva Torino
Jesper L Boldsen
Carmine Lubritto
ResearchOpen Access01 Sept 2015
Heritage Science

Volume: 3, P: 1-22
Late regulation of immune genes and microRNAs in circulating leukocytes in a pig model of influenza A (H1N2) infection

Louise Brogaard
Peter M. H. Heegaard
Kerstin Skovgaard
ResearchOpen Access19 Feb 2016
Scientific Reports

Volume: 6, P: 1-11

Search

Methicillin-resistant Staphylococcus aureus alters cell wall glycosylation to evade immunity

Gating and modulation of a hetero-octameric AMPA glutamate receptor

Identification of epilepsy-associated neuronal subtypes and gene expression underlying epileptogenesis

Whole-genome analysis of diverse Chlamydia trachomatis strains identifies phylogenetic relationships masked by current clinical typing

Diminishing benefits of urban living for children and adolescents’ growth and development

Dendritic structural plasticity and neuropsychiatric disease

A revised view of the role of CaMKII in learning and memory

Aberrant phase separation and nucleolar dysfunction in rare genetic diseases

Rescue of neuropsychiatric phenotypes in a mouse model of 16p11.2 duplication syndrome by genetic correction of an epilepsy network hub

Plant traits and associated ecological data from Afromontane grasslands of Maloti-Drakensberg, South Africa

Rising rural body-mass index is the main driver of the global obesity epidemic in adults

Ant-plant sociometry in the Azteca-Cecropia mutualism

Ancient DNA study reveals HLA susceptibility locus for leprosy in medieval Europeans

Neratinib protects pancreatic beta cells in diabetes

Recycling pathways in cold-water coral reefs: Use of dissolved organic matter and bacteria by key suspension feeding taxa

Comparison of trace element chemistry in human bones interred in two private chapels attached to Franciscan friaries in Italy and Denmark: an investigation of social stratification in two medieval and post-medieval societies

Convento di San Francesco a Folloni: the function of a Medieval Franciscan Friary seen through the burials

Late regulation of immune genes and microRNAs in circulating leukocytes in a pig model of influenza A (H1N2) infection

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