Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Choose more journals

Article type Check one or more article types to show results from those article types only.
Subject Check one or more subjects to show results from those subjects only.
Date Choose a date option to show results from those dates only.

Custom date range

Clear all filters
Sort by:
Showing 1–16 of 16 results
Advanced filters: Author: Phil Buckley Clear advanced filters

  • An analysis of 24,202 critical cases of COVID-19 identifies potentially druggable targets in inflammatory signalling (JAK1), monocyte–macrophage activation and endothelial permeability (PDE4A), immunometabolism (SLC2A5 and AK5), and host factors required for viral entry and replication (TMPRSS2 and RAB2A).

    • Erola Pairo-Castineira
    • Konrad Rawlik
    • J. Kenneth Baillie
    ResearchOpen Access
    Nature
    Volume: 617, P: 764-768

  • A global network of researchers was formed to investigate the role of human genetics in SARS-CoV-2 infection and COVID-19 severity; this paper reports 13 genome-wide significant loci and potentially actionable mechanisms in response to infection.

    • Mari E. K. Niemi
    • Juha Karjalainen
    • Chloe Donohue
    ResearchOpen Access
    Nature
    Volume: 600, P: 472-477

  • A genome-wide association study including over 76,000 individuals with schizophrenia and over 243,000 control individuals identifies common variant associations at 287 genomic loci, and further fine-mapping analyses highlight the importance of genes involved in synaptic processes.

    • Vassily Trubetskoy
    • Antonio F. Pardiñas
    • Jim van Os
    Research
    Nature
    Volume: 604, P: 502-508

  • Whole-genome sequencing, transcriptome-wide association and fine-mapping analyses in over 7,000 individuals with critical COVID-19 are used to identify 16 independent variants that are associated with severe illness in COVID-19.

    • Athanasios Kousathanas
    • Erola Pairo-Castineira
    • J. Kenneth Baillie
    ResearchOpen Access
    Nature
    Volume: 607, P: 97-103

  • In this Viewpoint article, five leading immunologists discuss the processes involved in the resolution of inflammation. Could drugs that promote pro-resolution pathways be more effective than drugs that block pro-inflammatory mediators in treating certain chronic inflammatory diseases? The contributors debate this and other key issues in the field.

    • Christopher D. Buckley
    • Derek W. Gilroy
    • Paul P. Tak
    Reviews
    Nature Reviews Immunology
    Volume: 13, P: 59-66

  • Prior studies have examined fixed traits that correlate with plant invasiveness. Here the authors use a database of population matrices to compare demographic traits of invasive species in their native and invaded ranges, finding that demographic amplification is an important predictor of invasiveness.

    • Kim Jelbert
    • Danielle Buss
    • Dave Hodgson
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-6

  • A horizon scan was used to explore possible impacts of robotics and automated systems on achieving the UN Sustainable Development Goals. Positive effects are likely. Iterative regulatory processes and continued dialogue could help avoid environmental damages and increases in inequality.

    • Solène Guenat
    • Phil Purnell
    • Martin Dallimer
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-10

  • A potential association between periodontitis, a chronic inflammatory disease characterized by loss of the periodontal ligament and alveolar bone, and systemic rheumatic diseases—particularly rheumatoid arthritis—has been suggested. Results from studies that support such a link are outlined in this article, as are causal and non-causal factors that could determine an association between the two conditions.

    • Paola de Pablo
    • Iain L. C. Chapple
    • Thomas Dietrich
    Reviews
    Nature Reviews Rheumatology
    Volume: 5, P: 218-224

  • Nucleation of quartz can take years under ambient conditions, and the harsh conditions needed to achieve faster nucleation on a useful timescale preclude formation of nanocrystalline phases. Here quartz nanoparticles are nucleated from microemulsions; subsequent refinement under mild hydrothermal conditions yields nanocrystalline quartz within days.

    • Phil Buckley
    • Natasha Hargreaves
    • Sharon Cooper
    ResearchOpen Access
    Communications Chemistry
    Volume: 1, P: 1-10