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Showing 1–3 of 3 results
Advanced filters: Author: Philip Mehler Clear advanced filters

  • Multiple plastid-derived signals have been proposed but not shown to move to the nucleus to promote plant acclimation to fluctuating light. Here the authors use a fluorescent hydrogen peroxide sensor to provide evidence that H2O2 is transferred directly from chloroplasts to nuclei to control nuclear gene expression.

    • Marino Exposito-Rodriguez
    • Pierre Philippe Laissue
    • Philip M. Mullineaux
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-11

  • Kidney disease is an underappreciated medical complication of anorexia nervosa. Further research is needed to clarify the mechanisms that drive kidney disease in patients who restrict caloric intake or engage in purging. Education and awareness are also needed, because kidney disease is often under-recognized by these patients and their clinicians.

    • Leah Puckett
    • Shoshana Mehler
    • Philip Mehler
    Comments & Opinion
    Nature Reviews Nephrology
    Volume: 18, P: 677-678

  • The Appropriate Blood Pressure Control in Diabetes (ABCD) study remains one of the most relevant sources of data on the vexed issue of optimum management of blood pressure in diabetic patients. This Review by trial investigators provides a more-comprehensive description of data that have emerged from this 5-year, randomized study of moderate versus intensive control of blood pressure using either a calcium channel blocker or an ACE inhibitor.

    • Robert W Schrier
    • Raymond O Estacio
    • William R Hiatt
    Reviews
    Nature Clinical Practice Nephrology
    Volume: 3, P: 428-438