Clb2 is a B-type cyclin essential for mitotic progression. Here, the authors found that the CLB2 mRNA localizes to the yeast bud via a cis-acting ZIP-code and She2/She3 transport machinery. This spatial regulation ensures proper cyclin protein levels, whereas its mislocalization perturbs division timing and bud size control.
- Anna Maekiniemi
- Philipp Savakis
- Evelina Tutucci
