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Showing 1–8 of 8 results

Advanced filters: Author: Philippe Collas Clear advanced filters

Multimodal epigenetic and enhancer network remodeling shape the transcriptional landscape of human beige adipocytes

Integrated multi-omics analysis reveals that white and beige adipocyte fates are regulated by distinct epigenetic mechanisms, with promoter remodeling and enhancer rewiring shaping thermogenic gene activation

Sarah Hazell Pickering
Natalia M. Galigniana
Nolwenn Briand
ResearchOpen Access08 Jan 2026
Communications Biology

P: 1-13
Reprogramming fibroblasts to express T-cell functions using cell extracts

Anne-Mari Håkelien
Helga B. Landsverk
Philippe Collas
Research01 May 2002
Nature Biotechnology

Volume: 20, P: 460-466
Long-range interactions between topologically associating domains shape the four-dimensional genome during differentiation

The authors identify the formation of dynamic topologically associating domain (TAD) cliques during differentiation and reprogramming. Their analysis indicates that TAD cliques stabilize heterochromatin at the nuclear periphery.

Jonas Paulsen
Tharvesh M. Liyakat Ali
Philippe Collas
Research22 Apr 2019
Nature Genetics

Volume: 51, P: 835-843
Long non-coding RNA HOTAIR regulates cytoskeleton remodeling and lipid storage capacity during adipogenesis

Evdokiia Potolitsyna
Sarah Hazell Pickering
Nolwenn Briand
ResearchOpen Access16 Jun 2022
Scientific Reports

Volume: 12, P: 1-9
Unrestrained ESCRT-III drives micronuclear catastrophe and chromosome fragmentation

Vietri et al. show that the micronucleus fails to restrain ESCRT-III spreading due to its small size, resulting in aberrant accumulation of ESCRT-III to drive micronuclear collapse and DNA fragmentation.

Marina Vietri
Sebastian W. Schultz
Coen Campsteijn
Research29 Jun 2020
Nature Cell Biology

Volume: 22, P: 856-867
A rapid micro chromatin immunoprecipitation assay (ChIP)

John Arne Dahl
Philippe Collas
Protocols29 May 2008
Nature Protocols

Volume: 3, P: 1032-1045
Cytoskeletal rearrangement precedes nucleolar remodeling during adipogenesis

Characterization of nuclear and nucleolar dynamics during adipogenic differentiation of human adipose stem cells points to nucleolar remodeling as an active, mechanoregulated mechanism triggered by cytoskeleton rearrangement.

Evdokiia Potolitsyna
Sarah Hazell Pickering
Nolwenn Briand
ResearchOpen Access15 Apr 2024
Communications Biology

Volume: 7, P: 1-11
Computational 3D genome modeling using Chrom3D

Chrom3D is a computational platform designed to simulate the spatial positioning of chromosome domains relative to each other and to the nuclear periphery, starting from, for example, chromosome conformation capture and lamin ChIP-sequencing data.

Jonas Paulsen
Tharvesh Moideen Liyakat Ali
Philippe Collas
Protocols26 Apr 2018
Nature Protocols

Volume: 13, P: 1137-1152