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Showing 1–3 of 3 results
Advanced filters: Author: Philippe Petry Clear advanced filters

  • Resident macrophages of the muscularis externa refine the enteric nervous system (ENS) early in life by pruning synapses and phagocytosing enteric neurons, and later switch to a neuro-supportive function, indicating that the ENS is governed by a dedicated population of resident macrophages that adapt to the timely needs of the ENS.

    • Maria Francesca Viola
    • Marta Chavero-Pieres
    • Guy Boeckxstaens
    Research
    Nature
    Volume: 618, P: 818-826

  • This study shows that Aβ from transgenic host tissue is able to enter and deposit within wild-type grafts via microglia, thus identifying microglia as carriers of Aβ deposition into previously unaffected brain tissue.

    • Paolo d’Errico
    • Stephanie Ziegler-Waldkirch
    • Melanie Meyer-Luehmann
    ResearchOpen Access
    Nature Neuroscience
    Volume: 25, P: 20-25

  • Michel Georges and colleagues identify a founder mutation in CCDC39 associated with primary ciliary dyskinesia in Old English Sheepdogs. They further show that mutations in human CCDC39 cause a similar phenotype and that CCDC39 is required for the assembly of inner dynein arms and the dynein regulatory complex.

    • Anne-Christine Merveille
    • Erica E Davis
    • Serge Amselem
    Research
    Nature Genetics
    Volume: 43, P: 72-78