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Showing 1–2 of 2 results
Advanced filters: Author: Pierre Khoueiry Clear advanced filters

  • Longitudinal data in electronic health records could be used to improve definitions of patient clusters and therefore inform precision medicine interventions. Here, the authors introduce VaDeSC-EHR, a machine learning model that uses patient longitudinal trajectories and time-to-event data to define clusters.

    • Jiajun Qiu
    • Yao Hu
    • Johann de Jong
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-14

  • How do transcription factors lead to defined developmental programs? The ways in which transcription factors act at enhancer elements and how enhancer activity is established during development are discussed in this Review, which brings together genetic and genomic evidence.

    • François Spitz
    • Eileen E. M. Furlong
    Reviews
    Nature Reviews Genetics
    Volume: 13, P: 613-626