Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Choose more journals

Article type Check one or more article types to show results from those article types only.
Subject Check one or more subjects to show results from those subjects only.
Date Choose a date option to show results from those dates only.

Custom date range

Clear all filters
Sort by:
Showing 1–3 of 3 results
Advanced filters: Author: Pierre-Alexandre Kaminski Clear advanced filters

  • The cyanophage S-2L incorporates 2-aminoadenine (Z) instead of adenine into its DNA, which still pairs with thymine forming a triple hydrogen bond. Here, the authors identify a third gene mazZ located between purZ and datZ that is required for 2-aminoadenine biosynthesis and determine the crystal structures of MazZ and PurZ. They further show that co-expression of these three genes in E.coli enables 2-aminoadenine incorporation into the bacterial genome.

    • Dariusz Czernecki
    • Frédéric Bonhomme
    • Marc Delarue
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-9

  • The cyanophage S-2L incorporates 2-aminoadenine (Z) instead of adenine (A) in its genome. Here, the authors provide an explanation for the absence of A in S-2L genome by identifying and characterising functionally and structurally both the HD phosphohydrolase (datZ) that specifically cleaves dATP, and the sole DNA primase-polymerase of S-2L, nonspecific of dATP or dZTP.

    • Dariusz Czernecki
    • Pierre Legrand
    • Marc Delarue
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-11

  • Many Gram-negative bacteria secrete exopolysaccharides via functionally homologous synthase-dependent systems. Here the authors use electron microscopy to reveal that biofilm-promoting cellulose in E. coli is secreted by a conserved multi-component secretion system with a megadalton-sized asymmetric architecture.

    • Petya Violinova Krasteva
    • Joaquin Bernal-Bayard
    • Jean-Marc Ghigo
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-10