Nature Search

In vivo site-specific engineering to reprogram T cells

Stable and cell-specific transgene expression can be achieved through in vivo site-specific integration of large DNA payloads using a two-vector system of enveloped delivery vehicles and adeno-associated viruses.

William A. Nyberg
Pierre-Louis Bernard
Justin Eyquem
ResearchOpen Access18 Mar 2026
Nature

P: 1-10
Characterization and forecast of global influenza subtype dynamics

A global analysis sheds light on the dynamics and features involved in influenza subtype composition in epidemic seasons between 2000 and 2023 and presents a series of tools to predict next year’s composition.

Francesco Bonacina
Pierre-Yves Boëlle
Chiara Poletto
ResearchOpen Access11 Mar 2026
Nature Health

Volume: 1, P: 390-402
Validation of an incremental field test for the direct assessment of peak oxygen uptake in wheelchair-dependent athletes

Agnès Vinet
Pierre-Louis Bernard
Jean-Paul Micallef
Research01 May 1996
Spinal Cord

Volume: 34, P: 288-293
Prospective multicentre study of upper respiratory mucosal transcriptomics reveals two major endotypes of critically ill COVID-19 patients

Bay et al. investigate upper respiratory mucosal transcriptomic profiles in critically ill COVID-19 patients infected with Omicron using an unsupervised clustering approach. Their study identifies two distinct immune response profiles, one characterised by enhanced innate and inflammatory activation compared with the other, highlighting the immune heterogeneity in severe COVID-19.

Pierre Bay
Laure Boizeau
Slim Fourati
ResearchOpen Access09 Mar 2026
Communications Medicine

P: 1-12
The tetraspanin CD9 controls migration and proliferation of parietal epithelial cells and glomerular disease progression

In both focal segmental glomerulosclerosis (FSGS) and crescentic glomerulonephritis (CGN), kidney injury is characterised by the invasion of glomerular tufts by parietal epithelial cells (PECs). Here Lazareth et al. identify the tetraspanin CD9 as a key regulator of PEC migration, and find its upregulation in FSGS and CGN contributes to kidney injury in both diseases.

Hélène Lazareth
Carole Henique
Pierre-Louis Tharaux
ResearchOpen Access24 Jul 2019
Nature Communications

Volume: 10, P: 1-17
Genetic and pharmacological inhibition of microRNA-92a maintains podocyte cell cycle quiescence and limits crescentic glomerulonephritis

Crescentic rapidly progressive glomerulonephritis is a severe form of glomerula disease characterized by podocyte proliferation and migration. Here Henique et al. demonstrate that inhibition of miRNA-92a prevents kidney failure by promoting the expression of CDK inhibitor p57^Kip2 that regulates podocyte cell cycle.

Carole Henique
Guillaume Bollée
Pierre-Louis Tharaux
ResearchOpen Access28 Nov 2017
Nature Communications

Volume: 8, P: 1-15
Nosocomial transmission clusters and lineage diversity characterized by SARS-CoV-2 genomes from two large hospitals in Paris, France, in 2020

Valentin Leducq
Aude Jary
Benoit Visseaux
ResearchOpen Access20 Jan 2022
Scientific Reports

Volume: 12, P: 1-10
Crystal growth in confinement

How confinement affects the growth of crystals is poorly understood. Experiments in which NaClO₃ and CaCO₃ crystals are grown close to a glass substrate now show that new molecular layers can form via the transport of mass through the liquid film at the crystal-substrate interface.

Felix Kohler
Olivier Pierre-Louis
Dag Kristian Dysthe
ResearchOpen Access16 Nov 2022
Nature Communications

Volume: 13, P: 1-8
Underdetection of cases of COVID-19 in France threatens epidemic control

Analyses of virological and surveillance data in France show that a substantial proportion of symptomatic cases of COVID-19 have remained undetected and that easily accessible and efficient testing is required to control the pandemic.

Giulia Pullano
Laura Di Domenico
Vittoria Colizza
Research21 Dec 2020
Nature

Volume: 590, P: 134-139
Clinical phenotypes and outcomes associated with SARS-CoV-2 variant Omicron in critically ill French patients with COVID-19

SARS-CoV-2 variant Omicron has been suggested to cause less severe disease. This prospective study shows that the clinical phenotype in patients infected with Omicron differs from patients infected with Delta but no association between Delta and Omicron including sublineages and mortality was observed.

Nicolas de Prost
Etienne Audureau
Slim Fourati
ResearchOpen Access12 Oct 2022
Nature Communications

Volume: 13, P: 1-12
Rapid decline of neutralizing antibodies against SARS-CoV-2 among infected healthcare workers

The humoral immune response to SARS-CoV-2 infection is not yet fully understood. Here, Marot et al. monitor the longitudinal profile and neutralizing activity of IgG, IgA, and IgM among 26 healthcare workers and provide evidence for a short-lasting humoral immune protection due to a decrease of neutralizing antibody titers within 3 months.

Stéphane Marot
Isabelle Malet
Anne-Geneviève Marcelin
ResearchOpen Access08 Feb 2021
Nature Communications

Volume: 12, P: 1-7
sST2 is a key outcome biomarker in COVID-19: insights from discovery randomized trial

David M. Smadja
Clément R. Massonnaud
Benjamin Leveau
ResearchOpen Access24 Apr 2025
Scientific Reports

Volume: 15, P: 1-16
ABO blood types and SARS-CoV-2 infection assessed using seroprevalence data in a large population-based sample: the SAPRIS-SERO multi-cohort study

Mélanie Deschasaux-Tanguy
Fabien Szabo de Edelenyi
Mathilde Touvier
ResearchOpen Access23 Mar 2023
Scientific Reports

Volume: 13, P: 1-7
Author Correction: Rapid decline of neutralizing antibodies against SARS-CoV-2 among infected healthcare workers

Stéphane Marot
Isabelle Malet
Anne-Geneviève Marcelin
Amendments and CorrectionsOpen Access10 May 2021
Nature Communications

Volume: 12, P: 1
Author Correction: Clinical phenotypes and outcomes associated with SARS-CoV-2 variant Omicron in critically ill French patients with COVID-19

Nicolas de Prost
Etienne Audureau
Slim Fourati
Amendments and CorrectionsOpen Access07 Dec 2022
Nature Communications

Volume: 13, P: 1
Heterologous expression of the N-acetylglucosaminyltransferase I dictates a reinvestigation of the N-glycosylation pathway in Chlamydomonas reinhardtii

Gaëtan Vanier
Pierre-Louis Lucas
Muriel Bardor
ResearchOpen Access31 Aug 2017
Scientific Reports

Volume: 7, P: 1-12
DOK1 and DOK2 regulate CD8 T cell signaling and memory formation without affecting tumor cell killing

Vladimir Laletin
Pierre-Louis Bernard
Jacques A. Nunès
ResearchOpen Access01 Jul 2024
Scientific Reports

Volume: 14, P: 1-10
Cumulative incidence of SARS-CoV-2 infection and associated risk factors among frontline health care workers in Paris: the SEROCOV cohort study

Pierre Hausfater
David Boutolleau
Florence Tubach
ResearchOpen Access04 May 2022
Scientific Reports

Volume: 12, P: 1-11
Intranasally administrated fusion-inhibitory lipopeptides block SARS-CoV-2 infection in mice and enable long-term protective immunity

Intranasally administrated fusion-inhibitory lipopeptides derived from the SARS-CoV-2 spike protect mice from different viral variants and induce cross-reactive immunity, offering a innovative antiviral approach against COVID-19

Said Mougari
Valérie Favède
Branka Horvat
ResearchOpen Access15 Jan 2025
Communications Biology

Volume: 8, P: 1-16
Association of SARS-CoV-2 infection with physical activity domains and types

Jérémy Vanhelst
Bernard Srour
Boris Pastorino
ResearchOpen Access06 Nov 2023
Scientific Reports

Volume: 13, P: 1-11
A French cohort for assessing COVID-19 vaccine responses in specific populations

Paul Loubet
Linda Wittkop
Odile Launay
Correspondence12 Jul 2021
Nature Medicine

Volume: 27, P: 1319-1321
Reconstructing the hydraulics of the world’s first industrial complex, the second century CE Barbegal watermills, France

Cees W. Passchier
Marcel Bourgeois
Christoph Spötl
ResearchOpen Access21 Oct 2020
Scientific Reports

Volume: 10, P: 1-14
SARS-CoV-2 infection prevalence and associated factors among primary healthcare workers in France after the third COVID-19 wave

Marie Pouquet
Dorine Decarreaux
Alessandra Falchi
ResearchOpen Access05 Mar 2024
Scientific Reports

Volume: 14, P: 1-12
Associations between symptoms of attention-deficit hyperactivity disorder, socioeconomic status and asthma in children

Makiko Omura
Samuele Cortese
Cédric Galera
ResearchOpen Access16 Apr 2024
npj Mental Health Research

Volume: 3, P: 1-8
Modeling the impact of national and regional lockdowns on the 2020 spring wave of COVID-19 in France

Jonathan Roux
Clément R. Massonnaud
Pascal Crépey
ResearchOpen Access01 Feb 2023
Scientific Reports

Volume: 13, P: 1-9
Meta-analysis of epigenome-wide associations between DNA methylation at birth and childhood cognitive skills

Doretta Caramaschi
Alexander Neumann
Gemma Sharp
ResearchOpen Access10 Feb 2022
Molecular Psychiatry

Volume: 27, P: 2126-2135
Predictive usefulness of RT-PCR testing in different patterns of Covid-19 symptomatology: analysis of a French cohort of 12,810 outpatients

Caroline Apra
Charlotte Caucheteux
Pascaline Villie
ResearchOpen Access27 Oct 2021
Scientific Reports

Volume: 11, P: 1-11

Search

In vivo site-specific engineering to reprogram T cells

Characterization and forecast of global influenza subtype dynamics

Validation of an incremental field test for the direct assessment of peak oxygen uptake in wheelchair-dependent athletes

Prospective multicentre study of upper respiratory mucosal transcriptomics reveals two major endotypes of critically ill COVID-19 patients

The tetraspanin CD9 controls migration and proliferation of parietal epithelial cells and glomerular disease progression

Genetic and pharmacological inhibition of microRNA-92a maintains podocyte cell cycle quiescence and limits crescentic glomerulonephritis

Nosocomial transmission clusters and lineage diversity characterized by SARS-CoV-2 genomes from two large hospitals in Paris, France, in 2020

Crystal growth in confinement

Underdetection of cases of COVID-19 in France threatens epidemic control

Clinical phenotypes and outcomes associated with SARS-CoV-2 variant Omicron in critically ill French patients with COVID-19

Rapid decline of neutralizing antibodies against SARS-CoV-2 among infected healthcare workers

sST2 is a key outcome biomarker in COVID-19: insights from discovery randomized trial

ABO blood types and SARS-CoV-2 infection assessed using seroprevalence data in a large population-based sample: the SAPRIS-SERO multi-cohort study

Author Correction: Rapid decline of neutralizing antibodies against SARS-CoV-2 among infected healthcare workers

Author Correction: Clinical phenotypes and outcomes associated with SARS-CoV-2 variant Omicron in critically ill French patients with COVID-19

Heterologous expression of the N-acetylglucosaminyltransferase I dictates a reinvestigation of the N-glycosylation pathway in Chlamydomonas reinhardtii

DOK1 and DOK2 regulate CD8 T cell signaling and memory formation without affecting tumor cell killing

Cumulative incidence of SARS-CoV-2 infection and associated risk factors among frontline health care workers in Paris: the SEROCOV cohort study

Intranasally administrated fusion-inhibitory lipopeptides block SARS-CoV-2 infection in mice and enable long-term protective immunity

Association of SARS-CoV-2 infection with physical activity domains and types

A French cohort for assessing COVID-19 vaccine responses in specific populations

Reconstructing the hydraulics of the world’s first industrial complex, the second century CE Barbegal watermills, France

SARS-CoV-2 infection prevalence and associated factors among primary healthcare workers in France after the third COVID-19 wave

Associations between symptoms of attention-deficit hyperactivity disorder, socioeconomic status and asthma in children

Modeling the impact of national and regional lockdowns on the 2020 spring wave of COVID-19 in France

Meta-analysis of epigenome-wide associations between DNA methylation at birth and childhood cognitive skills

Predictive usefulness of RT-PCR testing in different patterns of Covid-19 symptomatology: analysis of a French cohort of 12,810 outpatients

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