Nature Search

ALK2 mutation in a patient with Down's syndrome and a congenital heart defect

Irene C Joziasse
Kelly A Smith
Jeroen Bakkers
Research19 Jan 2011
European Journal of Human Genetics

Volume: 19, P: 389-393
Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation

John Chambers, Jaspal Kooner, Pim van der Harst, Shyong Tai, Paul Elliott, Jiang He, Norihiro Kato and colleagues performed a genome-wide association study of blood pressure phenotypes in individuals of European, East Asian and South Asian ancestry. They find trait-associated SNPs at 12 loci, some of which are associated with methylation at nearby CpG sites.

Norihiro Kato
Marie Loh
John C Chambers
Research21 Sept 2015
Nature Genetics

Volume: 47, P: 1282-1293
Interethnic analyses of blood pressure loci in populations of East Asian and European descent

Blood pressure (BP) is a major risk factor for cardiovascular disease and more than 200 genetic loci associated with BP are known. Here, the authors perform discovery GWAS for BP in East Asians and meta-analysis in East Asians and Europeans and report ancestry-specific BP SNPs and selection signals.

Fumihiko Takeuchi
Masato Akiyama
Norihiro Kato
ResearchOpen Access28 Nov 2018
Nature Communications

Volume: 9, P: 1-16
Inhibition of miR-25 improves cardiac contractility in the failing heart

Reduced activity of the calcium-transporting ATPase SERCA2a is a hallmark of heart failure; here, microRNAs that downregulate SERCA2a function are identified, and antagonism of one, miR-25, is shown to halt heart failure in mice.

Christine Wahlquist
Dongtak Jeong
Mark Mercola
Research12 Mar 2014
Nature

Volume: 508, P: 531-535
Unravelling fears of genetic discrimination: an exploratory study of Dutch HCM families in an era of genetic non-discrimination acts

Els Geelen
Klasien Horstman
Ine Van Hoyweghen
Research28 Mar 2012
European Journal of Human Genetics

Volume: 20, P: 1018-1023
Leukocyte TLR5 deficiency inhibits atherosclerosis by reduced macrophage recruitment and defective T-cell responsiveness

Guilielmus H.J.M. Ellenbroek
Gijs H.M. van Puijvelde
Saskia C.A. de Jager
ResearchOpen Access16 Feb 2017
Scientific Reports

Volume: 7, P: 1-10
Leukocyte-Associated Immunoglobulin-like Receptor-1 is regulated in human myocardial infarction but its absence does not affect infarct size in mice

Guilielmus H. J. M. Ellenbroek
Judith J. de Haan
Saskia C. A. de Jager
ResearchOpen Access21 Dec 2017
Scientific Reports

Volume: 7, P: 1-13
Monitoring of cell therapy and assessment of cardiac function using magnetic resonance imaging in a mouse model of myocardial infarction

Linda W van Laake
Robert Passier
Christine L Mummery
Protocols11 Oct 2007
Nature Protocols

Volume: 2, P: 2551-2567
Human cardiomyocyte progenitor cells differentiate into functional mature cardiomyocytes: an in vitro model for studying human cardiac physiology and pathophysiology

Anke M Smits
Patrick van Vliet
Marie-José Goumans
Protocols05 Feb 2009
Nature Protocols

Volume: 4, P: 232-243

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ALK2 mutation in a patient with Down's syndrome and a congenital heart defect

Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation

Interethnic analyses of blood pressure loci in populations of East Asian and European descent

Inhibition of miR-25 improves cardiac contractility in the failing heart

Unravelling fears of genetic discrimination: an exploratory study of Dutch HCM families in an era of genetic non-discrimination acts

Leukocyte TLR5 deficiency inhibits atherosclerosis by reduced macrophage recruitment and defective T-cell responsiveness

Leukocyte-Associated Immunoglobulin-like Receptor-1 is regulated in human myocardial infarction but its absence does not affect infarct size in mice

Monitoring of cell therapy and assessment of cardiac function using magnetic resonance imaging in a mouse model of myocardial infarction

Human cardiomyocyte progenitor cells differentiate into functional mature cardiomyocytes: an in vitro model for studying human cardiac physiology and pathophysiology

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