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Showing 1–27 of 27 results
Advanced filters: Author: Pippa J. Moore Clear advanced filters

  • An analysis of 24,202 critical cases of COVID-19 identifies potentially druggable targets in inflammatory signalling (JAK1), monocyte–macrophage activation and endothelial permeability (PDE4A), immunometabolism (SLC2A5 and AK5), and host factors required for viral entry and replication (TMPRSS2 and RAB2A).

    • Erola Pairo-Castineira
    • Konrad Rawlik
    • J. Kenneth Baillie
    ResearchOpen Access
    Nature
    Volume: 617, P: 764-768

  • A global network of researchers was formed to investigate the role of human genetics in SARS-CoV-2 infection and COVID-19 severity; this paper reports 13 genome-wide significant loci and potentially actionable mechanisms in response to infection.

    • Mari E. K. Niemi
    • Juha Karjalainen
    • Chloe Donohue
    ResearchOpen Access
    Nature
    Volume: 600, P: 472-477

  • Genome-wide ancient DNA data from individuals from the Middle Bronze Age to Iron Age documents large-scale movement of people from the European continent between 1300 and 800 bc that was probably responsible for spreading early Celtic languages to Britain.

    • Nick Patterson
    • Michael Isakov
    • David Reich
    Research
    Nature
    Volume: 601, P: 588-594

  • Coastal seaweed transported to the open ocean contributes up to 3–4% of the particulate organic carbon sinking into the deeper ocean, according to combined ecological and biogeochemical modelling.

    • Karen Filbee-Dexter
    • Albert Pessarrodona
    • Dorte Krause-Jensen
    Research
    Nature Geoscience
    Volume: 17, P: 552-559

  • Whole-genome sequencing, transcriptome-wide association and fine-mapping analyses in over 7,000 individuals with critical COVID-19 are used to identify 16 independent variants that are associated with severe illness in COVID-19.

    • Athanasios Kousathanas
    • Erola Pairo-Castineira
    • J. Kenneth Baillie
    ResearchOpen Access
    Nature
    Volume: 607, P: 97-103

  • To better understand the impacts of marine heatwaves in coastal ecosystems, this study examined the responses of habitat-forming species (macroalgae, seagrass, and corals) to heatwave events in 1322 areas across 85 marine ecoregions. The results suggest marine heatwaves play a key role in the decline of habitat-forming species globally, although some areas exhibit a level of resilience.

    • Kathryn E. Smith
    • Margot Aubin
    • Dan A. Smale
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-14

  • A new model of glacial isostatic adjustment used in conjunction with GRACE satellite data suggests that ice loss from Antarctica is contributing 0.19 millimetres per year to global mean sea level, which is substantially less than previous GRACE-based estimates.

    • Matt A. King
    • Rory J. Bingham
    • Glenn A. Milne
    Research
    Nature
    Volume: 491, P: 586-589

  • By combining fisheries, nutrient, and carbon cycling data, this synthesis suggests that marine kelp forests, a dominant but often undescribed habitat, provide services with a potential value of $111,000/ha/year and a global yearly value of $500 billion.

    • Aaron M. Eger
    • Ezequiel M. Marzinelli
    • Adriana Vergés
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-13

  • In 2023–2024, widespread marine heatwaves associated with record ocean temperatures impacted ocean processes, marine species, ecosystems and coastal communities, with economic consequences. Despite warnings, interventions were limited. Proactive strategies are needed for inevitable future events.

    • Kathryn E. Smith
    • Alex Sen Gupta
    • Dan A. Smale
    Comments & Opinion
    Nature Climate Change
    Volume: 15, P: 231-235

  • Metastatic melanoma is associated with a poor prognosis and understanding the genetic features of metastases may enable better treatment strategies. Here, the authors analyse multiple metastases from individual patients finding high levels of heterogeneity in metastases from different organs.

    • Roy Rabbie
    • Naser Ansari-Pour
    • David J. Adams
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-12

  • Marine heatwaves are climatic extremes with devastating and long-term impacts on marine ecosystems, fisheries and aquaculture. Here the authors use a range of ocean temperature observations to identify significant increases in marine heatwaves over the past century.

    • Eric C. J. Oliver
    • Markus G. Donat
    • Thomas Wernberg
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-12

  • Impacts from marine heatwaves can be devastating, but understanding their causes is largely based on case studies. Here the authors carry out a global assessment of literature and sea surface temperatures to identify important local processes, climate modes and teleconnections that drive marine heatwaves regionally.

    • Neil J. Holbrook
    • Hillary A. Scannell
    • Thomas Wernberg
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-13

  • Summarising CBD target 3 to “30 × 30” emphasizes area coverage, but conservation success depends on MPA quality. Many existing MPAs are under-protected, and rapidly designating new areas risks creating ‘paper parks’ without ecological or social benefits. Prioritizing strictly or fully managed MPAs, supported by a clear and shared definition, is essential to achieve meaningful biodiversity outcomes. Quality-focused strategies ensure that global targets benefit both nature and people, rather than merely meeting numerical goals.

    • Fabrice Stephenson
    • Barbara Horta e Costa
    • Joachim Claudet
    Comments & OpinionOpen Access
    npj Ocean Sustainability
    Volume: 4, P: 1-4

  • Marine heatwaves (MHWs) have become more intense and widespread globally, affecting species, ecosystems and people. After summarizing how and why MHWs are changing, this Review explores these impacts and their underlying mechanisms, highlights knowledge gaps and considers opportunities to mitigate the effects of MHWs.

    • Thomas Wernberg
    • Mads S. Thomsen
    • Katie Smith
    Reviews
    Nature Reviews Biodiversity
    Volume: 1, P: 461-479

  • Marine heatwaves are increasing in frequency, but they vary in their manifestation. All events impact ecosystem structure and functioning, with increased risk of negative impacts linked to greater biodiversity, number of species near their thermal limit and additional human impacts.

    • Dan A. Smale
    • Thomas Wernberg
    • Pippa J. Moore
    Research
    Nature Climate Change
    Volume: 9, P: 306-312

  • Global maps constructed using climate-change velocities to derive spatial trajectories for climatic niches between 1960 and 2100 show past and future shifts in ecological climate niches; properties of these trajectories are used to infer changes in species distributions, and thus identify areas that will act as climate sources and sinks, and geographical barriers to species migrations.

    • Michael T. Burrows
    • David S. Schoeman
    • Elvira S. Poloczanska
    Research
    Nature
    Volume: 507, P: 492-495

  • Research that combines all available studies of biological responses to regional and global climate change shows that 81–83% of all observations were consistent with the expected impacts of climate change. These findings were replicated across taxa and oceanic basins.

    • Elvira S. Poloczanska
    • Christopher J. Brown
    • Anthony J. Richardson
    Research
    Nature Climate Change
    Volume: 3, P: 919-925

  • Ocean warming will cause widespread changes in species richness and assemblage composition over coming decades, with important implications for both conservation management and international ocean governance.

    • Jorge García Molinos
    • Benjamin S. Halpern
    • Michael T. Burrows
    Research
    Nature Climate Change
    Volume: 6, P: 83-88

  • Three techniques for estimating mass losses from the Greenland Ice Sheet produce comparable results for the period 1992–2018 that approach the trajectory of the highest rates of sea-level rise projected by the IPCC.

    • Andrew Shepherd
    • Erik Ivins
    • Jan Wuite
    Research
    Nature
    Volume: 579, P: 233-239