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Showing 1–2 of 2 results
Advanced filters: Author: Polina N. Foteva Clear advanced filters

  • The histone deacylase SIRT7 regulates gene expression via highly specific activity on chromatin substrates. Moreno-Yruela et al. provide cryo-EM structures and identify the mechanisms of substrate specificity and a unique nucleosome-binding domain.

    • Carlos Moreno-Yruela
    • Babatunde E. Ekundayo
    • Beat Fierz
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-15

  • The endothelial to haematopoietic transition (EHT) is the process where haemogenic endothelium differentiates into haematopoietic stem and progenitor cells (HSPCs). Here the authors use single cell transcriptomics and antibody screening to identify CD44 as a marker of EHT that is required for EHT and HSPC development.

    • Morgan Oatley
    • Özge Vargel Bölükbası
    • Christophe Lancrin
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-18