Mazurkewich et al. report a phylogenetic, biochemical, and structural investigation of GH71 enzymes from Aspergillus nidulans, revealing distinct activities on α-1,3 glucooligosaccharides and roles in fungal cell wall remodeling. Their work uncovers the first GH71 structure with bound ligands, identifies a crucial DxxE catalytic dyad, and highlights the functional diversity of this poorly understood enzyme family.
- Scott Mazurkewich
- Tove Widén
- Johan Larsbrink
