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A redox-based electrogenetic CRISPR system to connect with and control biological information networks

Redox-responsive transcriptional regulators can enable user-specified electronic control over biological functions. Here the authors demonstrate electronic control of CRISPRa and CRISPRi using redox signalling.

Narendranath Bhokisham
Eric VanArsdale
William E. Bentley
ResearchOpen Access15 May 2020
Nature Communications

Volume: 11, P: 1-12
Bacterial co-culture with cell signaling translator and growth controller modules for autonomously regulated culture composition

To avoid metabolic overload and divide tasks, synthetic biologists are turning to microbial consortia engineering. Here the authors design a co-culture controller that autonomously regulates population composition.

Kristina Stephens
Maria Pozo
William E. Bentley
ResearchOpen Access11 Sept 2019
Nature Communications

Volume: 10, P: 1-11

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A redox-based electrogenetic CRISPR system to connect with and control biological information networks

Bacterial co-culture with cell signaling translator and growth controller modules for autonomously regulated culture composition

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