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Showing 1–3 of 3 results

Advanced filters: Author: Prisca Chapouton Clear advanced filters

Inceptor binds to and directs insulin towards lysosomal degradation in β cells

The insulin inhibitory receptor (inceptor) is found to bind to insulin and to regulate insulin stores by directing proinsulin and insulin towards lysosomal degradation.

Johanna Siehler
Sara Bilekova
Heiko Lickert
ResearchOpen Access25 Nov 2024
Nature Metabolism

Volume: 6, P: 2374-2390
Co-receptor regulation of insulin signaling

Decreased insulin action and insulin receptor signalling contribute to the pathology of diabetes. Liu et al. uncover a role for the Ephrin type-B receptor 4 in insulin receptor degradation regulating liver and systemic insulin sensitivity.

Prisca Chapouton
Heiko Lickert
News & Views21 Sept 2022
Nature Metabolism

Volume: 4, P: 1093-1094
Glial cells generate neurons: the role of the transcription factor Pax6

Nico Heins
Paolo Malatesta
Magdalena Götz
Research18 Mar 2002
Nature Neuroscience

Volume: 5, P: 308-315