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Showing 1–9 of 9 results

Advanced filters: Author: Qiaoshuai Lan Clear advanced filters

Human respiratory organoids sustained reproducible propagation of human rhinovirus C and elucidation of virus-host interaction

Difficulties in propagating HRV-C have hindered our understanding of this common respiratory pathogen. Here, authors developed an organoid-based system to reproducibly propagate HRV-C and characterized HRV-C infection in physiologically active respiratory organoids.

Cun Li
Yifei Yu
Jie Zhou
ResearchOpen Access30 Dec 2024
Nature Communications

Volume: 15, P: 1-13
The role of furin cleavage site in SARS-CoV-2 spike protein-mediated membrane fusion in the presence or absence of trypsin

Shuai Xia
Qiaoshuai Lan
Shibo Jiang
ResearchOpen Access12 Jun 2020
Signal Transduction and Targeted Therapy

Volume: 5, P: 1-3
Structure-based design of pan-coronavirus inhibitors targeting host cathepsin L and calpain-1

Xiong Xie
Qiaoshuai Lan
Hong Liu
ResearchOpen Access06 Mar 2024
Signal Transduction and Targeted Therapy

Volume: 9, P: 1-14
Antigenic mapping reveals sites of vulnerability on α-HCoV spike protein

The antigenic landscape of α-HCoVs S proteins is revealed, highlighting the challenges faced by pan-HCoV vaccine design but also revealing opportunities for development of broadly effective vaccines against a subset of HCoVs.

Jiangchao Xiang
Jie Su
Bei Yang
ResearchOpen Access04 Nov 2022
Communications Biology

Volume: 5, P: 1-13
Structural and functional basis for pan-CoV fusion inhibitors against SARS-CoV-2 and its variants with preclinical evaluation

Shuai Xia
Qiaoshuai Lan
Lu Lu
ResearchOpen Access29 Jul 2021
Signal Transduction and Targeted Therapy

Volume: 6, P: 1-10
Inhibition of SARS-CoV-2 (previously 2019-nCoV) infection by a highly potent pan-coronavirus fusion inhibitor targeting its spike protein that harbors a high capacity to mediate membrane fusion

Shuai Xia
Meiqin Liu
Lu Lu
ResearchOpen Access30 Mar 2020
Cell Research

Volume: 30, P: 343-355
Peptide-based pan-CoV fusion inhibitors maintain high potency against SARS-CoV-2 Omicron variant

Shuai Xia
Jasper Fuk-Woo Chan
Shibo Jiang
Correspondence27 Jan 2022
Cell Research

Volume: 32, P: 404-406
Structure-based evidence for the enhanced transmissibility of the dominant SARS-CoV-2 B.1.1.7 variant (Alpha)

Shuai Xia
Zuoling Wen
Yun Zhu
CorrespondenceOpen Access09 Nov 2021
Cell Discovery

Volume: 7, P: 1-5
Fusion mechanism of 2019-nCoV and fusion inhibitors targeting HR1 domain in spike protein

Shuai Xia
Yun Zhu
Lu Lu
CorrespondenceOpen Access11 Feb 2020
Cellular & Molecular Immunology

Volume: 17, P: 765-767