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Showing 1–5 of 5 results

Advanced filters: Author: Qicong Cao Clear advanced filters

Erratum: Methyltransferase Dnmt3a upregulates HDAC9 to deacetylate the kinase TBK1 for activation of antiviral innate immunity.

Xia Li
Qian Zhang
Xuetao Cao
Amendments and Corrections19 Jul 2016
Nature Immunology

Volume: 17, P: 1005
Methyltransferase Dnmt3a upregulates HDAC9 to deacetylate the kinase TBK1 for activation of antiviral innate immunity

The DNA methyltransferase Dnmt3a has not been studied in innate immunity. Cao and colleagues show that Dnmt3a enhances antiviral responses via a non-canonical mechanism to activate the kinase TBK1 and the production of type I interferons in macrophages.

Xia Li
Qian Zhang
Xuetao Cao
Research30 May 2016
Nature Immunology

Volume: 17, P: 806-815
Tet2 promotes pathogen infection-induced myelopoiesis through mRNA oxidation

A report of RNA 5-methylcytosine oxidation by mammalian Tet2, showing that Tet2 promotes infection-induced myelopoiesis in mice via a mechanism involving the repression of Socs3 mRNA, a previously unknown regulatory role of Tet2 at the epitranscriptomic level.

Qicong Shen
Qian Zhang
Xuetao Cao
Research24 Jan 2018
Nature

Volume: 554, P: 123-127
Multicenter analysis of the Mycoplasma pneumoniae resurgence in China 2023–2024

Mengyang Zhang
Wen Wen
Xiaoming Sun
ResearchOpen Access08 Dec 2025
Scientific Reports

Volume: 16, P: 1-9
Tet2 is required to resolve inflammation by recruiting Hdac2 to specifically repress IL-6

The Tet2 enzyme, which catalyses de novo hydroxymethylation of DNA, is shown here to act as a transcriptional repressor by recruiting the histone deacetylase Hdac2 to the Il6 promoter in the course of resolution of the LPS-induced inflammatory response.

Qian Zhang
Kai Zhao
Xuetao Cao
Research19 Aug 2015
Nature

Volume: 525, P: 389-393