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Showing 1–2 of 2 results
Advanced filters: Author: Quanhua Mu Clear advanced filters

  • Chemotherapy resistance in recurrent gliomas is a large hurdle for successful therapy. Here, the authors show that some recurrent gliomas harbour O-6-methylguanine-DNA methyltransferase (MGMT) genomic rearrangements, and in vitro and in vivo these contribute to temozolomide resistance.

    • Barbara Oldrini
    • Nuria Vaquero-Siguero
    • Massimo Squatrito
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-10

  • The location and timing of metastasis are still fundamentally unpredictable. Here the authors present the Metastatic Network model, a machine learning framework that integrates clinical data and DNA alterations to predict the risk of metastasis to specific organs as well as clinical outcomes

    • Biaobin Jiang
    • Quanhua Mu
    • Jiguang Wang
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-15