Meng et al. show that the RNA polymerase II elongation factor ELL3 suppresses the 5′ untranslated region activities of a subset of young LINE-1 elements, which activate genes such as Akt3, and regulate ERK signalling and naïve pluripotency in mouse embryonic stem cells.
- Siyan Meng
- Xiaoxu Liu
- Chengqi Lin
