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Nature Microbiology (1)

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The secreted kinase ROP17 promotes Toxoplasma gondii dissemination by hijacking monocyte tissue migration

The parasite Toxoplasma gondii secretes a virulence factor, the kinase ROP17 that modulates Rho–ROCK signalling in the infected host cell, enhancing monocyte motility on the surface of endothelial cells and inhibiting transmigration across endothelial barriers.

Lisa L. Drewry
Nathaniel G. Jones
L. David Sibley
Research22 Jul 2019
Nature Microbiology

Volume: 4, P: 1951-1963

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The secreted kinase ROP17 promotes Toxoplasma gondii dissemination by hijacking monocyte tissue migration

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