HCV mixed infection and reinfection occur commonly in people who inject drugs (PWID). The authors review the epidemiology, natural history and methods used to detect mixed HCV infection in PWID. The potential effect of mixed infection and reinfection on treatment outcomes is discussed, as well as how future studies should be designed in the era of direct acting antiviral treatment of HCV.
- Evan B. Cunningham
- Tanya L. Applegate
- Jason Grebely
