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Showing 1–50 of 281 results

Advanced filters: Author: R E Kleinman Clear advanced filters

SETD1A regulates psychiatric gene networks involved in genomic stability and synaptic function in rare and sporadic schizophrenia

Rare loss-of-function mutations in SETD1A are associated with schizophrenia, but how SETD1A haploinsufficiency leads to disease phenotypes remains unknown. Here, authors show that SETD1A regulates genes at common schizophrenia risk loci regulating genomic stability and synaptic function.

Tomoyo Sawada
Arthur S. Feltrin
Jennifer A. Erwin
ResearchOpen Access20 Dec 2025
Nature Communications

Volume: 17, P: 1-20
AIDS and the new drug injector

Drug injection is one way in which human immunodeficiency virus is transmitted. Health programmes should take into account epidemiological differences between more experienced and new drug injectors.

S. R. Friedman
A. Neaigus
Susan Tross
Research01 Jun 1989
Nature

Volume: 339, P: 333-334
Cytotoxic T lymphocyte mediated lysis without release of serine esterase

Hanne L. Ostergaard
Kevin P. Kane
William R. Clark
Research05 Nov 1987
Nature

Volume: 330, P: 71-72
Deregulation of Pax-2 expression in transgenic mice generates severe kidney abnormalities

Gregory R. Dressler
J. Erby Wilkinson
Heiner Westphal
Research01 Mar 1993
Nature

Volume: 362, P: 65-67
Passive Transplacental Immunization: Influence on the Detection of Enteric Antigen in the Systemic Circulation

R E Kleinman
P R Harmatz
W A Walker
Research01 Jun 1983
Pediatric Research

Volume: 17, P: 449-451
Long Term Effects on Immune Function of Early Nutritional Deprivation

D. G. JOSE
O. STUTMAN
R. A. GOOD
Research05 Jan 1973
Nature

Volume: 241, P: 57-58
Two distinct mechanisms of fibroblast adhesion

P. A. Harper
R. L. Juliano
Research12 Mar 1981
Nature

Volume: 290, P: 136-138
Collagen required for proliferation of cultured connective tissue cells but not their transformed counterparts

L. A. LIOTTA
D. VEMBU
C. BOONE
Research13 Apr 1978
Nature

Volume: 272, P: 622-624
Tethered epidermal growth factor as a paradigm for growth factor–induced stimulation from the solid phase

Philip R. Kuhl
Linda G Griffith-Cima
Research01 Sept 1996
Nature Medicine

Volume: 2, P: 1022-1027
Effect of Acute Polycythemia on Newborn Renal Hemodynamics and Function

Uma R Kotagal
Leonard I Kleinman
Research01 Feb 1982
Pediatric Research

Volume: 16, P: 148-151
Fibronectin in adhesion, spreading and cytoskeletal organization of cultured fibroblasts

I. Virtanen
T. Vartio
V.-P. Lehto
Research12 Aug 1982
Nature

Volume: 298, P: 660-663
Inter-hemispheric Transfer of Meaningful Visual Information in Normal Human Subjects

K. M. KLEINMAN
R. W. LITTLE
Research05 Jan 1973
Nature

Volume: 241, P: 55-57
Food Proteins and Gut Mucosal Barrier. III. The Influence of Lactation and Prolactin on the in Vitro Binding and Uptake of Bovine Serum Albumin and Ovalbumin in the Rat Jejunum

M Stern
P R Harmatz
W A Walker
Research01 Mar 1985
Pediatric Research

Volume: 19, P: 320-324
Laminin and fibronectin in rectal adenocarcinoma: Relationship to tumour grade, stage and metastasis

S J Forster
I C Talbot
D R Critchley
Research01 Jul 1984
British Journal of Cancer

Volume: 50, P: 51-61
Precipitated Electrons as a Cause of the Irregular Behaviour of the F₂ Region

MARSHA R. TORR
D. G. TORR
Research06 Jan 1968
Nature

Volume: 217, P: 45
Extinction by Interstellar Silica Grains

R. F. KNACKE
Research06 Jan 1968
Nature

Volume: 217, P: 44-45
A laminin-like adhesive protein concentrated in the synaptic cleft of the neuromuscular junction

Dale D. Hunter
Vandana Shah
Joshua R. Sanes
Research16 Mar 1989
Nature

Volume: 338, P: 229-234
Cross-species analysis of adult hippocampal neurogenesis reveals human-specific gene expression but convergent biological processes

Machine-learning-augmented single-nucleus transcriptomic analysis compared molecular landscapes of immature neurons in the mammalian hippocampus across species, highlighting human-specific gene expression but convergent biological processes.

Yi Zhou
Yijing Su
Hongjun Song
Research11 Aug 2025
Nature Neuroscience

Volume: 28, P: 1820-1829
Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders

Different functional variants in ADH1B (and elsewhere) in Europeans and Africans strongly affect risk for alcohol dependence. Dependence only partly genetically correlates with consumption, with strong correlations to other psychiatric disorders.

Raymond K. Walters
Renato Polimanti
Arpana Agrawal
Research26 Nov 2018
Nature Neuroscience

Volume: 21, P: 1656-1669
Neonatal outcomes following maternal red cell transfusions prior to or at delivery

Jeanne E. Hendrickson
Rebecca J. Birch
K. Malkin
Research12 Jan 2026
Journal of Perinatology

P: 1-3
Dopamine signaling enriched striatal gene set predicts striatal dopamine synthesis and physiological activity in vivo

Here, the authors report that schizophrenia risk variants mapping to a striatal dopamine-related gene set are associated with increased striatal dopamine synthesis capacity and increased striatal activity during reward anticipation in humans.

Leonardo Sportelli
Daniel P. Eisenberg
Giulio Pergola
ResearchOpen Access30 Apr 2024
Nature Communications

Volume: 15, P: 1-19
Climatic effects of Volcanic eruptions

MICHAEL R. RAMPINO
RICHARD B. STOTHERS
STEPHEN SELF
Research24 Jan 1985
Nature

Volume: 313, P: 272
Lack of correlation between tight junction morphology and permeability properties in developing choroid plexus (reply)

K. MOLLGARD
D. H. MALINOWSKA
N. R. SAUNDERS
Research12 May 1977
Nature

Volume: 267, P: 183
Genetic Analysis with Man–Mouse Somatic Cell Hybrids: Linkage between Human Lactate Dehydrogenase A and B and Peptidase B

F. H. RUDDLE
V. M. CHAPMAN
R. J. KLEBE
Research18 Jul 1970
Nature

Volume: 227, P: 251-257
Late Hyponatremia in Very Low Birthweight Infants (< 1.3 Kilograms)

R Neil Roy
G W Chance
J Sheepers
Research01 May 1976
Pediatric Research

Volume: 10, P: 526-531
Single-cell multi-ome and immune profiles of the Inspiration4 crew reveal conserved, cell-type, and sex-specific responses to spaceflight

Multiple omics platforms and deep single-cell profiling in the I4 astronauts reveal both conserved and distinct immune system disruptions across missions, provide a single-cell immune reference for future missions.

JangKeun Kim
Braden T. Tierney
Christopher E. Mason
ResearchOpen Access11 Jun 2024
Nature Communications

Volume: 15, P: 1-18
A human-specific AS3MT isoform and BORCS7 are molecular risk factors in the 10q24.32 schizophrenia-associated locus

eQTL analysis of human brain RNA-seq data targeted to genes within the 10q24.32 schizophrenia-associated locus reveals that the risk SNP in this region is selectively associated with expression of BORCS7 and a human-specific isoform of AS3MT across multiple independent samples. Expression of only the associated AS3MT isoform is higher in tissue from humans with schizophrenia than in healthy controls.

Ming Li
Andrew E Jaffe
Daniel R Weinberger
Research09 May 2016
Nature Medicine

Volume: 22, P: 649-656
Stimulation of p-Aminohippurate Extraction in the Maturing Rabbit Kidney

Matthew R Kaplan
John E Lewy
Research01 Aug 1978
Pediatric Research

Volume: 12, P: 834-837
Sex affects transcriptional associations with schizophrenia across the dorsolateral prefrontal cortex, hippocampus, and caudate nucleus

Schizophrenia research has traditionally overlooked sex differences. Here, the authors show the importance of sex-based analysis across multi-brain regions by identifying sex-specific genes and genetic interactions in schizophrenia and sex-specific risk.

Kynon J. M. Benjamin
Ria Arora
Jennifer A. Erwin
ResearchOpen Access10 May 2024
Nature Communications

Volume: 15, P: 1-16
Large-scale transcriptomic analyses of major depressive disorder reveal convergent dysregulation of synaptic pathways in excitatory neurons

Major Depressive Disorder (MDD) is a heritable psychiatric disorder whose biological basis remains poorly understood. This large-scale postmortem brain study identified extensive gene expression changes associated with genetic risk, highlighting disrupted glutamatergic signaling and synaptic vesicle function in MDD.

Fernando S. Goes
Leonardo Collado-Torres
Thomas M. Hyde
ResearchOpen Access28 Apr 2025
Nature Communications

Volume: 16, P: 1-15
Immune landscape of oncohistone-mutant gliomas reveals diverse myeloid populations and tumor-promoting function

Histone H3-mutant gliomas are deadly brain tumours and the tumour microenvironment is not fully understood. Here the authors profile the immune microenvironment from human samples and mouse models and implicate myeloid cells in immune suppression and show inhibition of myeloid cells and checkpoint blockade demonstrates therapeutic benefits in mice.

Augusto Faria Andrade
Alva Annett
Nada Jabado
ResearchOpen Access05 Sept 2024
Nature Communications

Volume: 15, P: 1-17
Renal Cation Excretion in the Hypocalcemic Premature Human Neonate

David R Brown
Betty H Steranka
Research01 Aug 1981
Pediatric Research

Volume: 15, P: 1100-1104
Genome-wide association meta-analysis highlights light-induced signaling as a driver for refractive error

Transancestral GWAS meta-analysis in 160,420 individuals identifies 139 loci associated with refractive error, including myopia. Newly identified genes implicate pathways involved in eye growth and light signaling cascades.

Milly S. Tedja
Robert Wojciechowski
Caroline C. W. Klaver
Research28 May 2018
Nature Genetics

Volume: 50, P: 834-848
Heparan sulphate bound growth factors: a mechanism for stromal cell mediated haemopoiesis

R. Roberts
J. Gallagher
T. M. Dexter
Research24 Mar 1988
Nature

Volume: 332, P: 376-378
Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences

A genetic study identifies hundreds of loci associated with risk tolerance and risky behaviors, finds evidence of substantial shared genetic influences across these phenotypes, and implicates genes involved in neurotransmission.

Richard Karlsson Linnér
Pietro Biroli
Jonathan P. Beauchamp
Research14 Jan 2019
Nature Genetics

Volume: 51, P: 245-257
Locally collective hydrogen bonding isolates lead octahedra for white emission improvement

Low dimensional lead halide perovskites possess intriguing optical properties that are still under debate. Here Cui et al. use hydrogen bonds containing spacers to synthesize highly luminescent perovskites with fully isolated lead-bromide octahedras and shed light on the origin of the emission.

Bin-Bin Cui
Ying Han
Qi Chen
ResearchOpen Access15 Nov 2019
Nature Communications

Volume: 10, P: 1-8
Functional replacement of the HIV-1 rev protein by the HTLV-1 rex protein

Laurence Rimsky
Joachim Hauber
Warner C. Greene
Research20 Oct 1988
Nature

Volume: 335, P: 738-740
Cholestatic Effect of Intraperitoneal Administration of Tryptophan to Suckling Rat Pups

Russell J Merritt
Frank R Sinatra
Harry Neustein
Research01 Sept 1984
Pediatric Research

Volume: 18, P: 904-907
K27M in canonical and noncanonical H3 variants occurs in distinct oligodendroglial cell lineages in brain midline gliomas

Comprehensive genomic profiling of human H3K27M mutant diffuse midline gliomas, combining single-cell RNA sequencing and ATAC sequencing with bulk ChIP sequencing and other data, proposes distinct oligodendrocyte populations as potential cells of origin.

Selin Jessa
Abdulshakour Mohammadnia
Claudia L. Kleinman
Research05 Dec 2022
Nature Genetics

Volume: 54, P: 1865-1880
Analysis of gene expression in the postmortem brain of neurotypical Black Americans reveals contributions of genetic ancestry

Studying gene expression in admixed Black Americans, Benjamin et al. reveal genetic ancestry-linked differences impacting immune and vascular genes and potentially influencing neurological disease risk. These findings highlight the importance of considering ancestry in brain research.

Kynon J. M. Benjamin
Qiang Chen
Daniel R. Weinberger
ResearchOpen Access20 May 2024
Nature Neuroscience

Volume: 27, P: 1064-1074
Surface sialic acid reduces attachment of metastatic tumour cells to collagen type IV and fibronectin

J. Dennis
C. Waller
V. Schirrmacher
Research18 Nov 1982
Nature

Volume: 300, P: 274-276
Stabilization of protein structure by interaction of α-helix dipole with a charged side chain

Das̆a S˘ali
Mark Bycroft
Alan R. Fersht
Research20 Oct 1988
Nature

Volume: 335, P: 740-743
Submillisecond optical pulsar in supernova 1987A

J. Kristian
C. R. Pennypacker
I. R. Tuohy
Research16 Mar 1989
Nature

Volume: 338, P: 234-236
Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals

Gene discovery and polygenic predictions from a genome-wide association study of educational attainment in 1.1 million individuals.

James J. Lee
Robbee Wedow
David Cesarini
Research23 Jul 2018
Nature Genetics

Volume: 50, P: 1112-1121
Raman evidence for pressure-induced formation of diamondene

The synthesis of two-dimensional diamond is the ultimate goal of diamond thin-film technology. Here, the authors perform Raman spectroscopy of bilayer graphene under pressure, and obtain spectroscopic evidence of formation of diamondene, an atomically thin form of diamond.

Luiz Gustavo Pimenta Martins
Matheus J. S. Matos
Luiz Gustavo Cançado
ResearchOpen Access21 Jul 2017
Nature Communications

Volume: 8, P: 1-9
No IR burst during a type I X-ray burst from the rapid burster (MXB1730–335)

K. Kawara
A. R. Hyland
R. J. Wainscoat
Research28 Jun 1984
Nature

Volume: 309, P: 770-771
On the size of the galactic centre compact radio source: diameter <20 AU

K. Y. Lo
D. C. Backer
J. M. Moran
Research09 May 1985
Nature

Volume: 315, P: 124-126
Stalled developmental programs at the root of pediatric brain tumors

A single-cell transcriptomic atlas from embryonal pons and forebrain provides insights into the developmental origins of pediatric brain tumors. The study identifies impaired differentiation of specific neural progenitors as a common mechanism underlying these cancers.

Selin Jessa
Alexis Blanchet-Cohen
Claudia L. Kleinman
Research25 Nov 2019
Nature Genetics

Volume: 51, P: 1702-1713
The Space Omics and Medical Atlas (SOMA) and international astronaut biobank

An integrated data and sample repository for clinical, cellular and multi-omics research from diverse spaceflight missions known as Space Omics and Medical Atlas (SOMA) is presented.

Eliah G. Overbey
JangKeun Kim
Christopher E. Mason
ResearchOpen Access11 Jun 2024
Nature

Volume: 632, P: 1145-1154
Cerebrovascular Hemodynamics during and after Recovery from Acute Asphyxia in the Newborn Dog

Andrew J McPhee
Uma R Kotagal
Leonard I Kleinman
Research01 Jul 1985
Pediatric Research

Volume: 19, P: 645-650

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