Nature Search

A benchmark of expert-level academic questions to assess AI capabilities

Humanity’s Last Exam, a multi-modal benchmark at the frontier of human knowledge, is designed to be an expert-level closed-ended academic benchmark with broad subject coverage.

Long Phan
Alice Gatti
Davide Scaramuzza
ResearchOpen Access28 Jan 2026
Nature

Volume: 649, P: 1139-1146
Boson sampling for molecular vibronic spectra

A quantum simulation scheme is proposed for molecular vibronic spectra, a problem for which no efficient classical algorithm is currently known. The simulation is efficiently performed on a boson sampling machine simply by modifying the input state.

Joonsuk Huh
Gian Giacomo Guerreschi
Alán Aspuru-Guzik
Research24 Aug 2015
Nature Photonics

Volume: 9, P: 615-620
Bose–Einstein Statistics and Helium Films

A. D. SINGH
R. K. PATHRIA
Research07 Mar 1959
Nature

Volume: 183, P: 668
The synaptic architecture of layer 5 thick tufted excitatory neurons in mouse visual cortex

This study maps the connections of layer 5 pyramidal neurons in the mouse cortex, revealing distinct local and intercortical wiring patterns, and provides an open framework for exploring the connectivity of cell types.

Agnes L. Bodor
Casey M. Schneider-Mizell
Nuno Maçarico da Costa
ResearchOpen Access28 Jul 2025
Nature Neuroscience

Volume: 28, P: 1704-1715
The architecture of EGFR’s basal complexes reveals autoinhibition mechanisms in dimers and oligomers

To prevent ligand-independent dimerisation the epidermal growth factor receptor (EGFR) is autoinhibited by an extracellular dimer interaction. Here, the authors use several imaging technologies and simulations to provide structural insights on the inactive species and on how intracellular mutations circumvent the autoinhibition of the basal state.

Laura C. Zanetti-Domingues
Dimitrios Korovesis
Marisa L. Martin-Fernandez
ResearchOpen Access18 Oct 2018
Nature Communications

Volume: 9, P: 1-17
Speciation and historical invasions of the Asian black-spined toad (Duttaphrynus melanostictus)

The Asian black-spined toad is a widespread, poisonous, invasive amphibian. Here, the authors use genomic and DNA-barcoding data from this toad to document its complex evolutionary history, two distinct species, and potential historic dispersal assisted by humans.

Christophe Dufresnes
Daniel Jablonski
Nikolay A. Poyarkov
ResearchOpen Access07 Jan 2025
Nature Communications

Volume: 16, P: 1-14
Human neocortical expansion involves glutamatergic neuron diversification

Combined patch clamp recording, biocytin staining and single-cell RNA-sequencing of human neurocortical neurons shows an expansion of glutamatergic neuron types relative to mouse that characterizes the greater complexity of the human neocortex.

Jim Berg
Staci A. Sorensen
Ed S. Lein
ResearchOpen Access06 Oct 2021
Nature

Volume: 598, P: 151-158
Survey of spiking in the mouse visual system reveals functional hierarchy

A large, open dataset containing parallel recordings from six visual cortical and two thalamic areas of the mouse brain is presented, from which the relative timing of activity in response to visual stimuli and behaviour is used to construct a hierarchy scheme that corresponds to anatomical connectivity data.

Joshua H. Siegle
Xiaoxuan Jia
Christof Koch
Research20 Jan 2021
Nature

Volume: 592, P: 86-92
EGFR oligomerization organizes kinase-active dimers into competent signalling platforms

Epidermal growth factor receptors have been shown to oligomerise upon binding to their cognate ligands. Here, the authors use biochemical, biophysical and cell biology techniques to analyse the structures of these oligomers, and argue that these formations are required for signalling.

Sarah R. Needham
Selene K. Roberts
Marisa L. Martin-Fernandez
ResearchOpen Access31 Oct 2016
Nature Communications

Volume: 7, P: 1-14
Unusual terahertz waveforms from a resonant medium controlled by diffractive optical elements

A. V. Pakhomov
R. M. Arkhipov
I. Babushkin
ResearchOpen Access15 May 2019
Scientific Reports

Volume: 9, P: 1-12
Classification of electrophysiological and morphological neuron types in the mouse visual cortex

Gouwens et al. established a morpho-electrical taxonomy of cell types for the mouse visual cortex via unsupervised clustering analysis of multiple quantitative features from 1,938 neurons available online at the Allen Cell Types Database.

Nathan W. Gouwens
Staci A. Sorensen
Christof Koch
Research17 Jun 2019
Nature Neuroscience

Volume: 22, P: 1182-1195
Author Correction: Human neocortical expansion involves glutamatergic neuron diversification

Jim Berg
Staci A. Sorensen
Ed S. Lein
Amendments and CorrectionsOpen Access06 Jan 2022
Nature

Volume: 601, P: E12
A large-scale standardized physiological survey reveals functional organization of the mouse visual cortex

By comparing neural responses to diverse visual stimuli measured with a standardized two-photon imaging pipeline, the authors reveal response specializations within the mouse visual cortex.

Saskia E. J. de Vries
Jerome A. Lecoq
Christof Koch
Research16 Dec 2019
Nature Neuroscience

Volume: 23, P: 138-151
Population density gratings induced by few-cycle optical pulses in a resonant medium

R. M. Arkhipov
A. V. Pakhomov
N. N. Rosanov
ResearchOpen Access29 Sept 2017
Scientific Reports

Volume: 7, P: 1-21
Modified Neuropixels probes for recording human neurophysiology in the operating room

This Protocol documents the extensive preparation required to adopt Neuropixels probes for use in patients for recording spiking activity from up to hundreds of cortical neurons and associating it with local field potentials.

Brian Coughlin
William Muñoz
Angelique C. Paulk
Protocols11 Sept 2023
Nature Protocols

Volume: 18, P: 2927-2953

Search

A benchmark of expert-level academic questions to assess AI capabilities

Boson sampling for molecular vibronic spectra

Bose–Einstein Statistics and Helium Films

The synaptic architecture of layer 5 thick tufted excitatory neurons in mouse visual cortex

The architecture of EGFR’s basal complexes reveals autoinhibition mechanisms in dimers and oligomers

Speciation and historical invasions of the Asian black-spined toad (Duttaphrynus melanostictus)

Human neocortical expansion involves glutamatergic neuron diversification

Survey of spiking in the mouse visual system reveals functional hierarchy

EGFR oligomerization organizes kinase-active dimers into competent signalling platforms

Unusual terahertz waveforms from a resonant medium controlled by diffractive optical elements

Classification of electrophysiological and morphological neuron types in the mouse visual cortex

Author Correction: Human neocortical expansion involves glutamatergic neuron diversification

A large-scale standardized physiological survey reveals functional organization of the mouse visual cortex

Population density gratings induced by few-cycle optical pulses in a resonant medium

Modified Neuropixels probes for recording human neurophysiology in the operating room

Search

Quick links

Search

Filter By:

Search

Quick links