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Showing 1–3 of 3 results
Advanced filters: Author: Rachel M. Rudlaff Clear advanced filters
  • Schizogony is essential for blood stage infection of Plasmodium parasites and produces several daughter cells. Here, Rudlaff et al. identify PfCINCH and interacting proteins as essential components of the basal complex required to establish daughter cell boundaries.

    • Rachel M. Rudlaff
    • Stephan Kraemer
    • Jeffrey D. Dvorin
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-13
  • Antibodies against Plasmodium falciparum glutamic-acid-rich protein (PfGARP), an antigen expressed on the surface of infected red blood cells, kill P. falciparum parasites by inducing programmed cell death and reduce the risk of severe malaria.

    • Dipak K. Raj
    • Alok Das Mohapatra
    • Jonathan D. Kurtis
    Research
    Nature
    Volume: 582, P: 104-108
  • The authors discover a pseudophosphatase that is an essential component of the basal complex, a contractile ring required for cell division of the malaria parasite. Using a combination of genetics, biochemistry, and cell biology techniques, they demonstrate that the pseudophosphatase, PfPPP8, is critical for integrity and contraction of the basal complex.

    • Alexander A. Morano
    • Rachel M. Rudlaff
    • Jeffrey D. Dvorin
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-17