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Communications Biology (1)

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Advanced filters: Author: Rahmawati Pare Clear advanced filters

Impairment of IgG Fc functions promotes tumor progression and suppresses NK cell antitumor actions

Single-hinge cleaved antibodies (scIgGs) in tumors damped NK cell cytotoxic activities and resulted in more aggressive tumor progression, which can be rescued by targeting the neoepitope in scIgGs with an anti-hinge antibody.

Xuejun Fan
Zihao Yuan
Ningyan Zhang
ResearchOpen Access14 Sept 2022
Communications Biology

Volume: 5, P: 1-14

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Impairment of IgG Fc functions promotes tumor progression and suppresses NK cell antitumor actions

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