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Showing 1–2 of 2 results
Advanced filters: Author: Raimon Duran-Struuck Clear advanced filters

  • A chemical screen identified a small molecule inhibitor of CHEK2 that boosts insulin secretion in human β cells, including those from both healthy and type 2 diabetic human islets, as well as in diabetic mouse models and cynomolgus macaques.

    • Angie Chi Nok Chong
    • J. Jeya Vandana
    • Shuibing Chen
    ResearchOpen Access
    Nature Chemical Biology
    Volume: 20, P: 566-576