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Showing 1–9 of 9 results
Advanced filters: Author: Randall H. Goldsmith Clear advanced filters

  • Binding of cAMP to hyperpolarization-activated cyclic nucleotide-gated (HCN) ion channels regulates cardiac pacemaking. Here, the authors examine the role of the lipid environment by reconstituting purified human HCN channels into lipid nanodiscs and measuring successive cAMP binding to single HCN channels.

    • Vinay Idikuda
    • Susovan Roy Chowdhury
    • Baron Chanda
    ResearchOpen Access
    Nature Communications
    P: 1-13

  • Direct monitoring of individual cAMP molecules binding to HCN ion channels reveals the binding dynamics underlying the distinct physiological responses of ion channel isoforms.

    • David S. White
    • Sandipan Chowdhury
    • Baron Chanda
    Research
    Nature
    Volume: 595, P: 606-610

  • Enhanced light–molecule interactions in high-finesse fibre-based Fabry–Pérot microcavities are used to detect and profile individual unlabelled solution-phase biomolecules, leading to potential applications in the life and chemical sciences.

    • Lisa-Maria Needham
    • Carlos Saavedra
    • Randall H. Goldsmith
    Research
    Nature
    Volume: 629, P: 1062-1068

  • Here the authors induce asymmetric transmission in planar Fabry–Pérot microcavities by embedding organic thin films exhibiting apparent circular dichroism (ACD), an optical phenomenon based on 2D chirality.

    • Tzu-Ling Chen
    • Andrew Salij
    • Randall H. Goldsmith
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-11

  • Single-particle double-modulation absorption spectrometers based on whispering-gallery-mode microresonators achieve sub-100-Hz sensitivity to photothermal resonance shifts and allow for the study of arrays of Fano resonances in the context of plasmonic–photonic hybridization.

    • Kevin D. Heylman
    • Niket Thakkar
    • Randall H. Goldsmith
    Research
    Nature Photonics
    Volume: 10, P: 788-795

  • A method for observing the photodynamics of single molecules, without having to immobilize them to a surface or confine them within vesicles, has been used to study the important photosynthetic antenna protein, allophycocyanin. Light-induced conformational changes and a complex relationship between fluorescence intensity and lifetime have been observed.

    • Randall H. Goldsmith
    • W. E. Moerner
    Research
    Nature Chemistry
    Volume: 2, P: 179-186

  • Molecular design and synthesis, from small molecules to supramolecular assemblies, combined with new spectroscopic probes of quantum coherence and theoretical modelling, offer a broad range of possibilities to realize practical quantum information science applications in computing, communications and sensing.

    • Michael R. Wasielewski
    • Malcolm D. E. Forbes
    • K. Birgitta Whaley
    Reviews
    Nature Reviews Chemistry
    Volume: 4, P: 490-504