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Advanced filters: Author: Rashelle Ghanem Clear advanced filters

  • Treatment of EGFR mutant non-small cell lung cancer (NSCLC) often develops resistance to EGFR TKIs. In this study, the authors discover a non-canonical activation of β-catenin signaling through Notch3 as a mechanism of adaptation to and resistance to EGFR TKI treatment in NSCLC.

    • Rajeswara Rao Arasada
    • Konstantin Shilo
    • David P. Carbone
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-16