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Skeletal muscle enhancer interactions identify genes controlling whole-body metabolism

Obesity and type 2 diabetes (T2D) are metabolic disorders characterized by insulin resistance in skeletal muscle. Here, the authors map skeletal muscle enhancer elements dynamically regulated after exposure to free fatty acid palmitate or inflammatory cytokine TNFα and identify target genes involved in metabolic dysfunction in skeletal muscle.

Kristine Williams
Lars R. Ingerslev
Romain Barrès
ResearchOpen Access01 Jun 2020
Nature Communications

Volume: 11, P: 1-16
Resequencing of 200 human exomes identifies an excess of low-frequency non-synonymous coding variants

Jun Wang and colleagues report the targeted capture and resequencing of the exomes of 200 Danish individuals at an average coverage of 12-fold. They identify an excess of low frequency non-synonymous variants that goes beyond previous predictions.

Yingrui Li
Nicolas Vinckenbosch
Jun Wang
Research03 Oct 2010
Nature Genetics

Volume: 42, P: 969-972
Ensure forest-data integrity for climate change studies

Risto Päivinen
Rasmus Astrup
Iddo K. Wernick
Correspondence22 May 2023
Nature Climate Change

Volume: 13, P: 495-496
A sensible climate solution for the boreal forest

Climate change could increase fire risk across most of the managed boreal forest. Decreasing this risk by increasing the proportion of broad-leaved tree species is an overlooked mitigation–adaption strategy with multiple benefits.

Rasmus Astrup
Pierre Y. Bernier
Ryan M. Bright
Comments & Opinion02 Jan 2018
Nature Climate Change

Volume: 8, P: 11-12
Climate targets in European timber-producing countries conflict with goals on forest ecosystem services and biodiversity

The role of increased timber harvests in reaching climate mitigation targets for European countries will be limited if the protection of forest ecosystem services and biodiversity is to be achieved, suggests an empirical forest model driven by future scenarios to limit warming to 1.5 °C in 2100.

Clemens Blattert
Mikko Mönkkönen
Kyle Eyvindson
ResearchOpen Access14 Apr 2023
Communications Earth & Environment

Volume: 4, P: 1-12
Cooling aerosols and changes in albedo counteract warming from CO₂ and black carbon from forest bioenergy in Norway

Anders Arvesen
Francesco Cherubini
Anders Hammer Strømman
ResearchOpen Access19 Feb 2018
Scientific Reports

Volume: 8, P: 1-13

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Skeletal muscle enhancer interactions identify genes controlling whole-body metabolism

Resequencing of 200 human exomes identifies an excess of low-frequency non-synonymous coding variants

Ensure forest-data integrity for climate change studies

A sensible climate solution for the boreal forest

Climate targets in European timber-producing countries conflict with goals on forest ecosystem services and biodiversity

Cooling aerosols and changes in albedo counteract warming from CO2 and black carbon from forest bioenergy in Norway

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Cooling aerosols and changes in albedo counteract warming from CO₂ and black carbon from forest bioenergy in Norway