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Showing 1–7 of 7 results
Advanced filters: Author: Rebecca Freilich Clear advanced filters

  • Genome-wide ancient DNA data from individuals from the Middle Bronze Age to Iron Age documents large-scale movement of people from the European continent between 1300 and 800 bc that was probably responsible for spreading early Celtic languages to Britain.

    • Nick Patterson
    • Michael Isakov
    • David Reich
    Research
    Nature
    Volume: 601, P: 588-594

  • Genomic analysis of Plasmodium DNA from 36 ancient individuals provides insight into the global distribution and spread of malaria-causing species during around 5,500 years of human history.

    • Megan Michel
    • Eirini Skourtanioti
    • Johannes Krause
    ResearchOpen Access
    Nature
    Volume: 631, P: 125-133

  • BAG3 is a Hsp70 co-chaperone that is highly expressed in muscles. Here the authors show that several myofibrillar myopathy causing BAG3 mutations are not impaired in Hsp70 binding, but rather impair the ADP-ATP exchange step of the Hsp70 cycle, causing the aggregation of BAG3, Hsp70 and Hsp70 clients and leading to a collapse of protein homeostasis.

    • Melanie Meister-Broekema
    • Rebecca Freilich
    • Harm H. Kampinga
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-14

  • Genome-wide data from 166 East Asian individuals dating to between 6000 bc and ad 1000 and from 46 present-day groups provide insights into the histories of mixture and migration of human populations in East Asia.

    • Chuan-Chao Wang
    • Hui-Yuan Yeh
    • David Reich
    Research
    Nature
    Volume: 591, P: 413-419

  • Ancient DNA reveals genetic differences between stone-tool users and people associated with ceramic technology in the Caribbean and provides substantially lower estimates of population sizes in the region before European contact.

    • Daniel M. Fernandes
    • Kendra A. Sirak
    • David Reich
    Research
    Nature
    Volume: 590, P: 103-110