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Showing 1–2 of 2 results
Advanced filters: Author: Rebecca M. Malcore Clear advanced filters

  • Stem cell quiescence is generally considered as an inactive state with poised potential. Here, Khoa et al. find that quiescent embryonic stem cells actively maintain a dynamic reservoir of cells with unrestricted cell fate that converges on S-adenosylmethionine and H3K27me3 status.

    • Le Tran Phuc Khoa
    • Wentao Yang
    • Yali Dou
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-19

  • Here the authors show eutherian mammals co-opted the histone demethylase KDM5C during sex-chromosome evolution to induce X-chromosome inactivation by upregulating Xist expression selectively in females.

    • Milan Kumar Samanta
    • Srimonta Gayen
    • Sundeep Kalantry
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-16