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Showing 1–6 of 6 results
Advanced filters: Author: Rebecca Mancusi Clear advanced filters

  • A phase I dose-escalation trial of GD2-CAR T cells in children and young adults with diffuse midline gliomas to assess the feasibility of manufacturing, safety and tolerability, and to preliminarily assess efficacy.

    • Robbie G. Majzner
    • Sneha Ramakrishna
    • Michelle Monje
    ResearchOpen Access
    Nature
    Volume: 603, P: 934-941

  • In glioma, malignant synapses hijack mechanisms of synaptic plasticity to increase glutamate-dependent currents in tumour cells and the formation of neuron–glioma synapses, thereby promoting tumour proliferation and progression.

    • Kathryn R. Taylor
    • Tara Barron
    • Michelle Monje
    ResearchOpen Access
    Nature
    Volume: 623, P: 366-374

  • Senescence of hematopoietic progenitor cells, enforced by the BRAFV600E mutation, underlies the development of Langerhans cell histiocytosis and could be a new target for drug development and therapy of this disease in patients.

    • Camille Bigenwald
    • Jessica Le Berichel
    • Miriam Merad
    Research
    Nature Medicine
    Volume: 27, P: 851-861

  • This Review examines the interplay between the nervous system and tumours, from cancer initiation to progression and metastasis.

    • Rebecca Mancusi
    • Michelle Monje
    Reviews
    Nature
    Volume: 618, P: 467-479