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Showing 1–2 of 2 results
Advanced filters: Author: Rehka T Clear advanced filters

  • Retrosynthetic pathway design using promiscuous enzymes can provide a solution to the biosynthetic production of natural products. Here, the authors design a pathway for the production of cis-α-irone with a promiscuous methyltransferase using structure-guided enzyme engineering strategies.

    • Xixian Chen
    • Rehka T
    • Isabelle André
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-10

  • Zhang et al. identified four linalool/nerolidol synthases from fungi using bioinformatics and phylogenetic analysis and validated their functions with in vitro and in vivo methods. One of them is a rare and highly specific monoterpene synthase and responsible for impressive titres of the commercially sought-after fragrance (R)-linalool.

    • Congqiang Zhang
    • Xixian Chen
    • Martin Rühl
    ResearchOpen Access
    Communications Biology
    Volume: 4, P: 1-11