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Showing 1–5 of 5 results

Advanced filters: Author: Reinhard Hinterleitner Clear advanced filters

A dendritic cell subset designed for oral tolerance

Studies using genetic tools have identified the distinct dendritic cell subsets that ensure tolerance to oral antigens in the antigen-rich environment of the gut and suggest a 'division of labor' for protective immunity.

Reinhard Hinterleitner
Bana Jabri
News & Views19 Apr 2016
Nature Immunology

Volume: 17, P: 474-476
Microbial signals drive pre-leukaemic myeloproliferation in a Tet2-deficient host

Microbial signals are crucial to the development of pre-leukaemic myeloproliferation, which can be induced by disrupting the intestinal barrier or by introducing systemic bacterial stimuli in Tet2-deficient mice.

Marlies Meisel
Reinhard Hinterleitner
Bana Jabri
Research16 May 2018
Nature

Volume: 557, P: 580-584
Antibiotic-induced perturbations in microbial diversity during post-natal development alters amyloid pathology in an aged APP_SWE/PS1_ΔE9 murine model of Alzheimer’s disease

Myles R. Minter
Reinhard Hinterleitner
Sangram S. Sisodia
ResearchOpen Access05 Sept 2017
Scientific Reports

Volume: 7, P: 1-18
The E3 ligase Cbl-b and TAM receptors regulate cancer metastasis via natural killer cells

The E3 ligase Cbl-b acts on TAM tyrosine kinase receptors and has a critical role in the regulation of natural killer (NK) cell rejection of metastatic tumours; a small molecule TAM kinase inhibitor is shown to enhance the anti-metastatic NK cell activity.

Magdalena Paolino
Axel Choidas
Josef M. Penninger
Research19 Feb 2014
Nature

Volume: 507, P: 508-512
Interleukin-15 promotes intestinal dysbiosis with butyrate deficiency associated with increased susceptibility to colitis

Marlies Meisel
Toufic Mayassi
Dionysios A Antonopoulos
Research20 Sept 2016
The ISME Journal

Volume: 11, P: 15-30