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Showing 1–2 of 2 results
Advanced filters: Author: Ren-Xi Wang Clear advanced filters

  • Regulatory B (Breg) cells producing interleukin-10 (IL-10) suppress autoimmune disease, but the mechanisms mediating their induction remain unclear. Charles E. Egwuagu and colleagues report that IL-35 induces Breg cells and also promotes their production of IL-35. In vivo IL-35 suppresses autoimmune disease in an IL-35 receptor– and IL-10–dependent manner. Adoptive transfer of IL-35–induced Breg cells inhibits established autoimmune disease, suggesting that IL-35 and IL-35–producing Breg cells may be used to treat inflammatory disease.

    • Ren-Xi Wang
    • Cheng-Rong Yu
    • Charles E Egwuagu
    Research
    Nature Medicine
    Volume: 20, P: 633-641

  • PPMC with a high Mn of up to 6.0 × 104 g mol−1 can be readily afforded under the catalysis of an immobilized lipase from Candida antarctica (Novozym-435). The result sounds attractive, as presently the low catalytic efficiency is known as the main restriction for the industrialization of enzyme catalysis.

    • Xiao-hua Luo
    • Jun Feng
    • Ren-xi Zhuo
    Research
    Polymer Journal
    Volume: 42, P: 722-727