Nature Search

Mental health conditions are associated with increased risk of subsequent self-harm, assault and unintentional injuries in two nations

In this two-nation administrative register study (~5 million individuals), mental health conditions were linked to subsequent unintentional, self-harm and assault injuries. These results highlight the need for targeted injury prevention strategies.

Leah S. Richmond-Rakerd
Barry J. Milne
Fartein Ask Torvik
ResearchOpen Access22 Dec 2025
Nature Mental Health

Volume: 4, P: 102-111
DNA methylation profiles of long-term cannabis users in midlife: a comprehensive evaluation of published cannabis-associated methylation markers in a representative cohort

Madeline H. Meier
Karen Sugden
Avshalom Caspi
ResearchOpen Access27 Jun 2025
Molecular Psychiatry

Volume: 30, P: 4576-4590
A nationwide analysis of 350 million patient encounters reveals a high volume of mental-health conditions in primary care

The authors present findings of more than 350 million primary-care visits over 14 years in the Norwegian healthcare system, indicating that 1 in 9 encounters involved a mental-health condition and peaking at age 40 years (18.7%).

Avshalom Caspi
Renate M. Houts
Fartein Ask Torvik
ResearchOpen Access19 Sept 2024
Nature Mental Health

Volume: 2, P: 1208-1216
Genetic associations with parental investment from conception to wealth inheritance in six cohorts

A study in 36,516 parents across six international cohorts reveals that parental genetic effects are associated with the investments that parents make in their offspring, from adopting more healthy behaviours during pregnancy to leaving wealth to adult children.

Jasmin Wertz
Terrie E. Moffitt
Avshalom Caspi
ResearchOpen Access29 Jun 2023
Nature Human Behaviour

Volume: 7, P: 1388-1401
Clustering of health, crime and social-welfare inequality in 4 million citizens from two nations

Using administrative data on 4 million citizens from two nations, Richmond-Rakerd et al. find that multiple health and social problems cluster in a population segment with low workforce readiness, including low education and poor early-life mental health.

Leah S. Richmond-Rakerd
Stephanie D’Souza
Terrie E. Moffitt
Research20 Jan 2020
Nature Human Behaviour

Volume: 4, P: 255-264
Disparities in the pace of biological aging among midlife adults of the same chronological age have implications for future frailty risk and policy

A cohort study tracking 20-year age-related declines in multiple organ systems finds that, already by midlife, those aging fastest showed cognitive declines, signs of brain aging, diminished sensory–motor function and negative views about aging.

Maxwell L. Elliott
Avshalom Caspi
Terrie E. Moffitt
Research15 Mar 2021
Nature Aging

Volume: 1, P: 295-308
Childhood forecasting of a small segment of the population with large economic burden

By linking data from a 40-year birth cohort study with multiple administrative databases, the authors show that 20% of the population accounts for close to 80% of economic burden. Strikingly, this group can be predicted with high accuracy from as early as 3 years old.

Avshalom Caspi
Renate M. Houts
Terrie E. Moffitt
Research12 Dec 2016
Nature Human Behaviour

Volume: 1, P: 1-10
Replicability of structural brain alterations associated with general psychopathology: evidence from a population-representative birth cohort

Adrienne L. Romer
Annchen R. Knodt
Ahmad R. Hariri
ResearchOpen Access03 Dec 2019
Molecular Psychiatry

Volume: 26, P: 3839-3846
Genetics and the geography of health, behaviour and attainment

Data from a cohort of US and UK adolescents reveal that genetic and neighbourhood risks for early pregnancy and educational attainment are correlated, but find a weak or no correlation between risks for obesity or schizophrenia.

Daniel W. Belsky
Avshalom Caspi
Candice L. Odgers
Research08 Apr 2019
Nature Human Behaviour

Volume: 3, P: 576-586
Establishing a generalized polyepigenetic biomarker for tobacco smoking

Karen Sugden
Eilis J. Hannon
Avshalom Caspi
ResearchOpen Access15 Feb 2019
Translational Psychiatry

Volume: 9, P: 1-12

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