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Advanced filters: Author: Renping Qiao Clear advanced filters

  • The cell cycle regulatory E3 ligase APC/C cooperates with UBE2C to prime substrates with ubiquitin and UBE2S to extend the ubiquitin chains. Careful analysis reveals that binding of the UBE2S to APC/C accelerates the rate-limiting step of APC/C–UBE2C.

    • Raquel C. Martinez-Chacin
    • Tatyana Bodrug
    • Nicholas G. Brown
    Research
    Nature Structural & Molecular Biology
    Volume: 27, P: 550-560