Companion diagnostics using biomarkers are promising for guiding radiotherapy, but biopsy-based techniques normally fail to detect real-time variations in target response and tumor heterogeneity. Herein, the authors report an activated afterglow/MRI probe as a companion diagnostics tool for dynamically assessing biomarker apurinic/apyrimidinic endonuclease 1(APE1) during radiotherapy in vivo.
- Renye Yue
- Zhe Li
- Guosheng Song
