A pH-responsive superwetting surface is fabricated and applied as a point-of-care testing platform for naked eye biosensing. Because of the outstanding switching between superhydrophilicity and superhydrophobicity, contact angle based biosensing method is developed for pH, urea, and glucose detection. Especially, non-invasive detection of glucose is achieved for diabetes diagnosis and exercise monitoring. Given to its low cost, instrument-free, disposable, and rapid response (within 1 s), this strategy not only provides a universal platform of point-of-care testing but also extends the industrial-scale application of bioinspired superwettability systems.
- Zhong Feng Gao
- Ei Ei Sann
- Lei Jiang
