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Showing 1–4 of 4 results
Advanced filters: Author: Reut E. Avraham Clear advanced filters

  • Chen et al. show that PEX39 cooperates with PEX7 in the peroxisomal import of proteins containing a PTS2 site and uncover an (R/K)PWE motif in PEX39 and PEX13 that binds to PEX7 and facilitates the import of PTS2-containing proteins.

    • Walter W. Chen
    • Tony A. Rodrigues
    • Bettina Warscheid
    ResearchOpen Access
    Nature Cell Biology
    Volume: 27, P: 1256-1271

  • Enkler et al. show that a pool of Arf1 at lipid droplets is implicated in mitochondrial ATP production control through regulation of fatty acid metabolism and acetyl-CoA transfer to mitochondria.

    • Ludovic Enkler
    • Viktoria Szentgyörgyi
    • Anne Spang
    ResearchOpen Access
    Nature Cell Biology
    Volume: 25, P: 1157-1172

  • Here, the authors generate a replication-competent VSV based vaccine expressing SARS-CoV-2 spike protein and show protection in the hamster model with one dose. Analysis of the antibody response in mice shows induction of neutralizing antibodies and suggests a desirable Th1-biased response to the vaccine.

    • Yfat Yahalom-Ronen
    • Hadas Tamir
    • Tomer Israely
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-13

  • Here, using the K18-hACE2 transgenic mice model, the authors report the in vivo efficacy of a fully human neutralizing antibody against SARS-CoV-2 and show that when administered before or up to 3 days post infection, treated mice do not exhibit disease symptoms while 80% of control animals succumb to the infection.

    • Ronit Rosenfeld
    • Tal Noy-Porat
    • Ohad Mazor
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-9