The sea anemone Nematostella vectensis expresses miRNAs and two Argonaute (AGO) proteins. Here the authors show that NveAGO1 and NveAGO2 are loaded with overlapping but different sets of miRNAs and that NveAGO2 binds both miRNAs and endo-siRNAs. Both AGO proteins are essential for development.
- Arie Fridrich
- Vengamanaidu Modepalli
- Yehu Moran
