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Advanced filters: Author: Richard Buksch Clear advanced filters
  • Familial dysautonomia is linked to mutations in IKBKAP, a scaffolding protein for the Elongator complex, which regulates codon-biased gene translation in yeast. Here the authors show in mammalian neurons that IKBKAP loss alters expression of codon-biased genes, including some involved in DNA damage.

    • Joy Goffena
    • Frances Lefcort
    • Lynn George
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-10