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Advanced filters: Author: Rikako Ukichi Clear advanced filters

  • ROCK2 is found to be activated in 3 diabetic models and patients with diabetes. ROCK2 deletion in podocytes protects against diabetic kidney injury, with the beneficial effect of ROCK2 inhibition observed due to rescued PPARα signaling, leading to a recovery of fatty acid metabolism.

    • Keiichiro Matoba
    • Yusuke Takeda
    • Rimei Nishimura
    ResearchOpen Access
    Communications Biology
    Volume: 5, P: 1-9